Publications by authors named "Yu-heng Shi"
Article Synopsis
- Scientists have found that spinal cord injuries are hard to treat, so they are looking for new drugs to help heal them.
- Researchers discovered a new substance called VD11 from a special frog that helps nerve cells grow and repair in lab tests and in injured rats.
- The study suggests that VD11 works by activating certain pathways in the body that help with recovery after spinal cord injuries.
Colorectal cancer has the second highest incidence of malignant tumors and is the fourth leading cause of cancer deaths in China. Early diagnosis and treatment of colorectal cancer will lead to an improvement in the 5-year survival rate, which will reduce medical costs. The current diagnostic methods for early colorectal cancer include excreta, blood, endoscopy, and computer-aided endoscopy.
View Article and Find Full Text PDFAims: Obstructive sleep apnea (OSA) is a risk factor for steroid-resistant (SR) asthma. However, the underlying mechanism is not well defined. This study aimed to investigate how chronic intermittent hypoxia (CIH), the main pathophysiology of OSA, influenced the effects of glucocorticoids (GCs) on asthma.
View Article and Find Full Text PDFArticle Synopsis
- * It finds that patients with moderate to severe asthma have fewer Treg cells and lower levels of interleukin-10 compared to healthy individuals, while Th2 cells and interleukin-4 are higher.
- * The results suggest that an imbalance favoring Th2 cells over Treg cells could contribute to the worsening of asthma symptoms in these patients.
In order to investigate the characteristics of the microbial degradation of tetrabromobisphenol A (TBBPA), four aerobic strains were isolated from the phenol granular sludge using selective medium with TBBPA as the sole carbon source. Among them, strain H could accommodate the TBBPA culture medium and degrade TBBPA with high efficiency, which was identified as Rhodococcus sp. via DNA sequencing test.
View Article and Find Full Text PDF[Characteristics of histone deacetylase 9 in peripheral blood of patients with bronchial asthma].
Zhonghua Jie He He Hu Xi Za Zhi
May 2012
Objective: To investigate the expression pattern of histone deacetylase 9 (HDAC9) in peripheral blood of asthmatics and its effect on immune cells (Th2, Th17, Tregs) involved in the pathogenesis of asthma.
Methods: Forty-seven asthmatics from Ruijin Hospital were recruited and assigned to intermittent, mild and moderate-severe groups. Lung function test and Asthma Control Questionnaire were performed to evaluate asthma control and severity.
Background: Recent recognition is that Th2 response is insufficient to fully explain the aetiology of asthma. Other CD4(+) T cells subsets might play a role in asthma. We investigated the relative abundance and activities of Th1, Th2, Th17 and CD4(+)CD25(+) Treg cells in patients with allergic asthma.
View Article and Find Full Text PDF[CD(4)(+)T cells and immunological therapy of bronchial asthma].
Zhonghua Jie He He Hu Xi Za Zhi
October 2010