A meta-analysis and systematic review based on perioperative management of elderly patients: is ciprofol an alternative to propofol?

Purpose: With the rising number of elderly surgical patients, selecting an appropriate anesthetic tailored to their specific needs is essential. Ciprofol, a novel intravenous anesthetic, has garnered attention due to its low injection pain rate and minimal impact on the circulatory system. This meta-analysis aims to examine the efficacy and safety profile of ciprofol during perioperative management of elderly patients.

Tick salivary protein Cystatin: structure, anti-inflammation and molecular mechanism.

Ticks are blood-sucking ectoparasites that secrete immunomodulatory substances in saliva to hosts during engorging. Cystatins, a tick salivary protein and natural inhibitor of Cathepsins, are attracting growing interest globally because of the immunosuppressive activities and the feasibility as an antigen for developing anti-tick vaccines. This review outlines the classification and the structure of tick Cystatins, and focuses on the anti-inflammatory effects and molecular mechanisms.

[Effects of desflurane on auditory evoked potential index and quantitative electroencephalogram].

Objective: To observe the effects of desflurane on A-line ARX Index (AAI), QEEG, MAP and HR, and to investigate the feasibility of AAI, QEEG, MAP and HR in monitoring the depth of anesthesia with desflurane.

Methods: Thirty patients classified as ASA physical status I approximately II were scheduled for elective lower abdominal surgery. Anesthesia was induced with propofol and vecuronum.