Improvement of triterpenoid production in mycelia of through mutagenesis breeding and amelioration of CCl-induced liver injury in mice.

Due to the scarcity of wild fruiting bodies, submerged fermentation of the medicinal fungus is attracting much attention, but the production of bioactive triterpenoids is low. Therefore, there is an urgent need to improve the triterpenoid yield of submerged fermentation. Here, the mutant E3-64 was generated from strain AC16101 through random mutagenesis breeding, producing 172.

[Effects of long-term different fertilization patterns on soil nutrients and microbial community structure of tomato in a solar greenhouse.].

The phospholipid fatty acid (PLFA) technique was used to investigate the effects of fertilization on soil characteristics and microbial community of tomato in a solar greenhouse in Shouguang, Shandong Province, China, based on a long-term (12-year) fertilization experiment. The experiment involved a control (CK) and five fertilization treatments, namely, traditional nitrogen application (CN), traditional nitrogen application+straw return (CNS), optimized nitrogen application (SN), optimized nitrogen application+straw return (SNS), and organic manure nitrogen application+straw return (MNS). Results showed that the contents of soil organic matter and avai-lable P and K under all fertilization treatments were significantly higher than that of CK, but no significant difference among fertilization treatments.

[Effect of angong niuhuang pill as an adjuvant treatment on moderate or severe neonatal hypoxic-ischemic Encephalopathy].

Objective: To evaluate the clinical efficacy and safety of angong niuhuang pill (ANP) as an adjuvant treatment on moderate or severe neonatal hypoxic-ischemic encephalopathy (NHIE).

Methods: Thirty-nine neonates with NHIE in the control group were treated with conventional treatment, and 58 in the treated group were administered orally ANP additionally, and relative indexes were observed.

Results: The improvement of aspects such as recovery of consciousness, muscular tension, and primitive reflex and disappearance of convulsion, in the treated group was better than that in the control group (P < 0.