Publications by authors named "Yu-Zhen He"
Delayed neurocognitive recovery after surgery is associated with increased morbidity and mortality. However, its mechanism of action remains controversial and complex. A prospective, double-blind, randomized controlled trial was performed at the Affiliated Hospital of Zunyi Medical University.
View Article and Find Full Text PDF(AR) has multiple pharmacological activities to prevent and treat Alzheimer's disease (AD). However, the effect and its molecular mechanism are not elucidated clear. This study aims to evaluate AR's therapeutic effect and mechanism on AD model rats induced by -galactose and AlCl with serum metabolomics.
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- The study investigates whether smoking is an independent risk factor for postoperative cognitive impairment in patients undergoing general anesthesia.
- It involved 112 patients undergoing painless gastroscopy where baseline cognitive scores were measured, and changes were observed immediately after anesthesia and three days post-op.
- Results showed significant cognitive differences immediately after anesthesia between smokers and non-smokers, with smoking linked to increased postoperative cough and potentially contributing to cognitive dysfunction in early postoperative recovery.