Publications by authors named "Yu-Ze Ge"
Article Synopsis
- MYB-NFIB fusion and NOTCH1 mutation are common in salivary gland adenoid cystic carcinoma (SACC), but abnormal expression of these genes can also occur in patients without these mutations.
- This study used single-cell RNA sequencing to analyze two SACC patients lacking MYB-NFIB fusion and NOTCH1 mutation, identifying 25 cell types and highlighting the Notch signaling pathway in cancer cells.
- The research demonstrated that all-trans retinoic acid (ATRA) can suppress lung metastasis in SACC by correcting faulty cell differentiation linked to abnormal NOTCH1 or MYB expression, suggesting its potential role in SACC diagnosis and treatment.
