Publications by authors named "Yu-Yun Kuo"
The mitochondrial genome (mitogenome) (Matsumura, 1909), an endemic moth species in Taiwan, was sequenced and analyzed. The complete circular mitogenome of is 15,303 bp and contains 13 protein-coding genes, 22 transfer RNA genes, 2 ribosomal RNA genes, and an AT-rich control region. The mitogenome has an overall nucleotide composition of 41.
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- Hidradenitis suppurativa (HS) severely affects patients' quality of life and often faces challenges due to delayed diagnosis, necessitating better understanding of its key disease mediators.
- Research identified interleukin-17A (IL-17A) as a critical factor in HS, with bioinformatic analyses revealing elevated IL-17A+ mast cells in HS skin, especially in advanced stages.
- Treatments targeting IL-17A, such as biologics, effectively reduced disease severity and IL-17A+ mast cell density, suggesting that these cells could serve as a diagnostic marker and potential therapeutic target for HS.
Aims: Glioblastoma multiforme (GBM) is the most aggressive and mortal primary glioma in adults. Temozolomide (TMZ) is a first-line clinical chemotherapeutic drug. However, TMZ resistance causes treatment failure in patients.
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