Publications by authors named "Yu-Yu Dai"
Article Synopsis
- A series of 1,4-naphthoquinone derivatives were created and analyzed as potential anti-cancer agents, with the crystal structure of one compound confirmed through X-ray diffraction.
- Testing on four cancer cell lines revealed that one compound displayed significant cytotoxicity specifically on the A549 cell line, with an IC value of 6.15 μM.
- Further studies indicated that this compound induced autophagy by enhancing EGFR recycling and activating its signaling pathway, suggesting a promising approach for developing new anti-cancer drugs.
