Publications by authors named "Yu-Ying Chou"
Article Synopsis
- Patients with Alzheimer’s and related tauopathies show increased neuronal excitability, leading to early onset of symptoms and potential for early treatment intervention.
- Research aims to uncover how pathological tau influences this excitability, which could reveal new therapeutic targets.
- Using a novel method involving CaMPARI2 and CRISPRi, researchers are screening over 3000 genes to identify genetic modifiers impacting neuronal activity in tauopathies.
Background: Fatigue has been identified as a major symptom in heart transplant (HTx) patients; however, researchers have not examined the role of fatigue characteristics (ie, intensity, interference, and duration) in the quality of life (QOL) of HTx patients.
Objective: The aim of this study was to explore differences in physical and mental aspects of QOL by patient characteristics, as well as the association between fatigue characteristics and QOL in HTx patients after considering other confounding factors (symptom distress and psychological distress).
Methods: A cross-sectional study was conducted in which patients completed the Transplant Symptom Frequency and Symptom Distress Scale, the Fatigue Symptom Inventory, the Hospital Anxiety and Depression Scale, and the 12-item Short-Form Health Survey.