Publications by authors named "Yu-Yang Chang"

Article Synopsis
  • Peptidoglycan (PG) sacculi protect cells by maintaining their shape and stability against pressure, with enzymes called endopeptidases helping to modify the structure during growth.
  • The adaptor protein NlpI interacts with the endopeptidase MepS, facilitating the organization and enhanced activity of MepS in breaking down PG.
  • Additionally, the complex formation between NlpI, MepS, and the protease Prc indicates that NlpI not only enhances MepS activity but also aids in its degradation, showing a crucial regulatory mechanism in PG synthesis and turnover.
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Background And Objectives: Considering the pulse widths of picosecond and nanosecond lasers used in cutaneous laser surgery differ by approximately one order of magnitude, can nanosecond lasers produce the optical effect in human skin similar to laser-induced optical breakdown (LIOB) caused by picosecond lasers?

Methods: Cutaneous changes induced by a focused fractional nanosecond 1064-nm Nd:YAG laser were evaluated by VISIA-CR imaging, histological examination, and harmonic generation microscopy (HGM).

Results: A focused fractional nanosecond 1064-nm Nd:YAG laser can generate epidermal vacuoles or dermal cavities similar to the phenomenon of LIOB produced by picosecond lasers. The location and extent of photodisruption can be controlled by the laser fluence and focus depth.

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In this study, a multi-objective optimization of directed energy deposition (DED) process was conducted with Taguchi-Grey relational analysis. The used part was designed as a flat rectangle which would be deposited by a single-layer and multi-track DED process. Firstly, after finishing Taguchi experiments, the effects of five control factors (laser power, overlap ratio, powder feed rate, scanning speed and laser defocus distance) on three DED product qualities (cladding efficiency, surface roughness and porosity) were, respectively, analyzed.

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