, gen. et sp. nov. (Boletaceae), a bolete with flocculent-covered stipe from northern China.

Some collections from northern China are proposed as the new genus and species based on morphological assessments and molecular phylogenetic evidence. It is circumscribed by the pink pileus, white context turning pale blue to bule when exposed, yellow hymenophore surface turning blue when bruised, stipe covered with plenty of flocculent hairs, ellipsoid-fusiform to subfusiform smooth basidiospores, and the presence of hymenial cystidia. Phylogenetic analyses inferred from four gene fragments (28S, , and ) revealed a distinct position of this new genus in Boletaceae, but no place to accommodate it at subfamily rank.

, a new genus of Gomphales.

The genus and species are proposed as new based on morphological assessments and molecular phylogenetic evidence inferred from nucleotide sequences of mitochondrial (mt) adenosine triphosphate (ATPase) subunit 6 () and mt small subunit rDNA (mtSSU). Basidiomes of are characterized by the peach to pinkish orange color, cantharelloid habit with a gill-like hymenophore with obtuse edges, smooth and cylindrical to allantoid basidiospores, and cylindrical to narrowly clavate flexuous pleurocystidia. The species resembles a species of but differs from the latter by the cylindrical basidiospores.

Two new species from North China revealed by phylogenetic analyses and morphological characters.

Two new species of are proposed based on morphological and phylogenetic investigations. is closely related to but distinguished from the latter by its slightly smaller basidiospores and hyphae of pileipellis with pale brown to brown intracellular or parietal pigment. is closely related to and in macromorphology but is differentiated from by its slightly smaller basidiospores and the difference in genetic profile, and from by its relatively colorful pileus (white to yellowish white, grayish white to grayish brown, pink white).

New Species and New Records of from China Based on Molecular and Morphological Data.

Species of genus previously reported in China are mainly distributed in the northeast, northwest and southwest regions of China, but the species diversity of in north China is not very clear. In this study, newly collected specimens from northern China and some herbarium specimens deposited in three important Chinese fungus herbaria (HMAS, HKAS, HMJAU) were studied using morphological and phylogenetic methods. The internal transcribed spacers of the nrDNA (ITS), the nrRNA 28S subunit (nrLSU), the translation elongation factor 1-alpha (), and the second largest subunit of RNA polymerase II (), were employed to elucidate the phylogenetic relationships between species.

New Species of and from North China.

Within the family Inocybaceae, many species of and have been reported, but there are only a few reports on these two genera from north China. In this study, six collections of and 11 collections of were studied by morphological and phylogenetic methods. Phylogenetic analyses based on sequence data from three or two different loci (ITS, LSU, and for ; ITS and LSU for ) are performed to infer species relationships within genera and , respectively.

BAP1 loss augments sensitivity to BET inhibitors in cancer cells.

The tumor suppressor gene BAP1 encodes a widely expressed deubiquitinase for histone H2A. Both hereditary and acquired mutations are associated with multiple cancer types, including cutaneous melanoma (CM), uveal melanoma (UM), and clear cell renal cell carcinoma (ccRCC). However, there is no personalized therapy for BAP1-mutant cancers.

Expression levels of chemokine (C-X-C motif) ligands CXCL1 and CXCL3 as prognostic biomarkers in rectal adenocarcinoma: evidence from Gene Expression Omnibus (GEO) analyses.

Rectal cancer is a life‑threatening disease worldwide. Chemotherapy resistance is common in rectal adenocarcinoma patients and has unfavorable survival outcomes; however, its related molecular mechanisms remain unknown. To identify genes related to the initiation and progression of rectal adenocarcinoma, three datasets were obtained from the Gene Expression Omnibus database.

A taxonomic reassessment of the genus from China.

Molecular analysis of the genus was conducted with ITS and 28S sequences available, including newly gained sequences from Chinese specimens. Combined with the morphological examinations, a new hypogeous species, was described and illustrated from North China, which is morphologically characterized by reddish brown ascomata covered with fine warts, the whitish gleba with numerous small chambers, 3-5 layers peridium with reddish brown polygonal cells and the smooth and regular ellipsoid ascospores with one large oil drop. Two species previously described as were transferred to .

[Biological exposure limits caused by co exposure to fluoride and arsenic based on Wnt signaling pathway].

Chronic fluoride-arsenic combined poisoning is a global public health problem. While the cause of the disease is clear, the pathogenesis is unknown. Given that there is no specific treatment, early prevention is particularly important.

Correction: A possible new mechanism and drug intervention for kidney damage due to arsenic poisoning in rats.

[This corrects the article DOI: 10.1039/C5TX00165J.].

A possible new mechanism and drug intervention for kidney damage due to arsenic poisoning in rats.

Arsenic poisoning is a worldwide endemic disease that affects thousands of people. Currently, the aetiology of the disease is known, but its pathogenesis is uncharacterized and there is no specific treatment. We established a rat model of coal-burning arsenic poisoning by feeding the animals corn powder baked with high arsenic coal.

Arsenic may be involved in fluoride-induced bone toxicity through PTH/PKA/AP1 signaling pathway.

Chronic exposure to combined fluoride and arsenic continues to be a major public health problem worldwide, affecting thousands of people. In recent years, more and more researchers began to focus on the interaction between the fluorine and the arsenic. In this study, the selected investigation site was located in China.

[The establishment of the arsenic poisoning rats model caused by corn flour baked by high-arsenic coal].

Objective: To establish coal arsenic poisoning rat model by feeding the rats with the corn powder baked by high arsenic coal as the main raw material.

Methods: Fifty Wistar rats, healthy, were randomly divided into 5 groups according to the figures of their weights, including control group, drinking arsenic poisoning water group, low, medium and high arsenic contaminated grain group, 10 rats for each.Rats in control group and drinking arsenic poisoning water group were fed with standard feed without any arsenic containing.