In Vitro and In Vivo Antimelanogenesis Effects of Leaf Essential Oil from .

species are widely distributed around Southeast Asia, Australasia, South Pacific islands, and etc. Traditionally, species have been used as the folk medicines, the common ethnopharmacological uses of genus are the treatments of headache and myalgia. This study aims to investigate the chemical composition of (Lamb.

Cytotoxicity and Apoptosis Induction of 6,7-Dehydroroyleanone from Bark Essential Oil in Hepatocellular Carcinoma Cells.

The objective of the present study is to evaluate the cytotoxicity of essential oil and its phytochemical on the Hep G2 cell line (human hepatocellular carcinoma). Bark essential oil has significant cytotoxicity to Hep G2 cells, and S3 fraction is the most active fraction in cytotoxicity to Hep G2 cells among the six fractions. The diterpenoid quinone, 6,7-dehydroroyleanone, was isolated from the active S3 fraction by bioassay-guided isolation.

Antimelanogenesis Effects of Leaf Extract and Phytochemicals from Ceylon Olive () in Zebrafish Model.

The melanogenesis inhibition effect in zebrafish () and antityrosinase activity of the ethanolic extract and its phytochemicals from Ceylon olive ( Linn.) leaves were investigated in this study. Among the leaf extract and four soluble fractions, the ethyl acetate soluble fraction exhibits the best antityrosinase and antimelanogenesis activities.