Publications by authors named "Yu-Ting Lin"

Tantalum disulfide (1T-TaS), being a Mott insulator with strong electron correlation, is highlighted for diverse collective quantum states in the 2D lattice, including charge density wave (CDW), spin liquid, and unconventional superconductivity. The Mott physics embedded in the 2D triangular CDW lattice has raised debates on stacking-dependent properties because interlayer interactions are sensitive to van der Waals (vdW) spacing. However, control of interlayer distance remains a challenge.

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  • The management of diabetic wounds is difficult, but extracellular vesicles (EVs) from human adipose-derived stem cells (hASCs) show potential for treatment despite challenges with their quantity and quality.
  • A novel method using cell spheroids to culture hASCs successfully increased the yield and angiogenic properties of the EVs, leading to improved wound healing characteristics.
  • In vivo tests on diabetic rats demonstrated that these enhanced EVs significantly improved collagen production, wound closure, and blood vessel formation, suggesting a promising new approach for treating diabetic wounds.
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  • - The study evaluated the effects of auricular acupressure on sleep quality, mood, and quality of life among parents of kids with cancer, using a three-week intervention with two groups: an active treatment group and a sham group.
  • - Results showed 78% adherence to the acupressure protocol, with no overall differences in sleep quality or mood, but significant improvements in quality of life and vigor for the active treatment group at certain times.
  • - The findings suggest potential benefits of the intervention, although a larger study is needed to confirm effectiveness for parents dealing with cancer-related stress.
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Background: Liver cancer stands as a leading cause of cancer-related deaths globally, challenging conventional treatments due to resistance to chemotherapy and targeted therapy. Although frontline medications show initial efficacy, prolonged use often leads to resistance and harm. Current clinical strategies rely on combination therapies, but evaluating their effectiveness remains challenging.

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  • - The study investigates "pinhead," a condition affecting farmed fish like milkfish, characterized by extreme weight loss and lack of appetite, comparing it to healthy and starved fish.
  • - Results show that pinhead milkfish exhibit lower overall health metrics and signs of internal water imbalance, with high levels of the anorexigenic hormone leptin A, possibly contributing to their anorexia.
  • - This research highlights the physiological impacts of pinhead condition for the first time, indicating a need for further exploration of stress factors leading to this issue and potential solutions to improve fish health.
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  • A new vardenafil analogue was found during testing of a dietary supplement for impurities.
  • The compound was extracted and analyzed using advanced techniques like liquid chromatography-high resolution mass spectrometry (LC-HRMS) and nuclear magnetic resonance (NMR).
  • It was named 19-O-propyl hydroxy vardenafil, indicating it has specific modifications including a hydroxyl group and a propyl group in its structure.
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  • Eccentric exercise training (EET) is shown to enhance physical performance with lower metabolic strain compared to concentric exercise training (CET), but its impact on bioenergetic efficiency in peripheral blood mononuclear cells (PBMCs) is not well understood.
  • In a study involving 33 sedentary males, participants were assigned to either EET, CET, or a control group, with both exercise groups demonstrating improved aerobic fitness and physiological responses post-intervention.
  • Both EET and CET increased beneficial T cell types and mitochondrial functions in PBMCs, suggesting that EET may offer similar benefits to CET while eliciting a lower cardiovascular response.
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We investigated the photoinduced relaxation of Kasha-type emitting ruthenium-(bidentate cyclometalated aromatic ligand), Ru-CM, chromophores of [Ru(pzpy)(CM)] ions (CM = 1-phenylisoquinoline, 2,3-diphenylpyrazine, and 1,4-diazatriphenylene and pzpy = 2-pyrazol-1-yl-pyridine). This is the first report of the phosphorescence behavior of pure Ru-(bidentate CM) chromophores. The 77 K photoinduced relaxation characteristics of phosphorescence chromophores showed emission quantum yields higher than those of reference Ru-bpy (bpy = 2,2'-bipyridine) chromophores in the emission region of 670-900 nm.

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Digoxin, a cardiac glycoside drug, is commonly used to treat heart failure and arrhythmias. The therapeutic concentration range of digoxin, with a narrow therapeutic index, is between 0.5 and 2.

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Current genome-wide association studies (GWAS) for kidney function lack ancestral diversity, limiting the applicability to broader populations. The East-Asian population is especially under-represented, despite having the highest global burden of end-stage kidney disease. We conducted a meta-analysis of multiple GWASs (n = 244,952) on estimated glomerular filtration rate and a replication dataset (n = 27,058) from Taiwan and Japan.

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  • A study investigated how residential noise exposure affects burnout among 5,416 healthcare workers in Taiwan between 2012 and 2017.
  • Burnout was measured using the Mandarin Copenhagen Burnout Inventory, with results indicating that increased noise levels correlated with higher burnout scores.
  • The findings suggest a strong association, with each increase of 1 dBA in noise linked to significant rises in both personal and work-related burnout levels.
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Controlling the growth of halide perovskite films under high relative humidity (RH) ambient conditions is significant for practical applications. Here, we control the antisolvent-assisted growth reactions with a constant temperature and low RH. With the hot casting setup and antisolvent during growth reactions, the synthesis of high coverage and pinhole-free CsPb(Br,I) films is achieved in ambient air.

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  • The research compares the effectiveness of ultrasound-guided suprascapular nerve block (SSNB) to intraarticular corticosteroid injections (IACI) for treating frozen shoulder in a trial involving 76 patients.
  • Both treatment groups showed significant improvements in shoulder pain and function, but the IACI group generally performed better, particularly in specific measures of pain and range of motion.
  • The study results suggest that while both treatments are effective, IACIs may offer superior outcomes compared to SSNB, especially regarding pain relief and shoulder movement.
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We investigated fluctuations of the photoplethysmography (PPG) waveform in patients undergoing surgery. There is an association between the morphologic variation extracted from arterial blood pressure (ABP) signals and short-term surgical outcomes. The underlying physiology could be the numerous regulatory mechanisms on the cardiovascular system.

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Major advances have been made in utilizing human-induced pluripotent stem cells (hiPSCs) for regenerative medicine. Nevertheless, the delivery and integration of hiPSCs into target tissues remain significant challenges, particularly in the context of retinal ganglion cell (RGC) restoration. In this study, we introduce a promising avenue for providing directional guidance to regenerated cells in the retina.

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Dialysis patients often have inadequate health literacy, affecting self-care and outcomes. This study used LINE app to provide personalized health education to Taiwanese dialysis patients and collected physiological data via wearables. While physical activity levels remained unchanged, participants' disease literacy significantly improved post-intervention.

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Continuous biosensors measure concentration-time profiles of biomolecular substances in order to allow for comparisons of measurement data over long periods of time. To make meaningful comparisons of time-dependent data, it is essential to understand how measurement imprecision depends on the time interval between two evaluation points, as the applicable imprecision determines the significance of measured concentration differences. Here, we define a set of measurement imprecisions that relate to different sources of variation and different time scales, ranging from minutes to weeks, and study these using statistical analyses of measurement data.

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Background And Objectives: Nintedanib, a tyrosine kinase inhibitor, is integral in slowing pulmonary fibrosis progression in chronic fibrotic interstitial lung disease (ILD). However, the occurrence of adverse drug reactions (ADRs) often limits its use, leading to treatment discontinuation, typically within 3-12 months. Discontinuation adversely affects patient outcomes.

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In pursuing sustainable thermal insulation solutions, this study explores the integration of human hair and feather keratin with alginate. The aim is to assess its potential in thermal insulation materials, focusing on the resultant composites' thermal and mechanical characteristics. The investigation uncovers that the type and proportion of keratin significantly influence the composites' porosity and thermal conductivity.

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Brain oscillations are crucial for perception, memory, and behavior. Parvalbumin-expressing (PV) interneurons are critical for these oscillations, but their population dynamics remain unclear. Using voltage imaging, we simultaneously recorded membrane potentials in up to 26 PV interneurons in vivo during hippocampal ripple oscillations in mice.

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Biosensors based on immobilized antibodies require molecular strategies that (i) couple the antibodies in a stable fashion while maintaining the conformation and functionality, (ii) give outward orientation of the paratope regions of the antibodies for good accessibility to analyte molecules in the biofluid, and (iii) surround the antibodies by antibiofouling molecules. Here, we demonstrate a method to achieve oriented coupling of antibodies to an antifouling poly(l-lysine)--poly(ethylene glycol) (PLL--PEG) substrate, using glycan remodeling to create antibody-DNA conjugates. The coupling, orientation, and functionality of the antibodies were studied using two analysis methods with single-molecule resolution, namely single-molecule localization microscopy and continuous biosensing by particle motion.

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Objective: We describe a rare case of uterine mesothelial cysts mimicking ovarian cysts in a primipara patient with a history of Cesarean section.

Case Report: A 39-year-old female patient with history of Cesarean section presented with dysmenorrhea. Sonography revealed that a hypoechoic and anechoic multicystic complex, which was located on the right side of the pelvic cavity, had infiltrated the adjacent posterior wall of the uterus, and it was preoperatively misdiagnosed as ovarian cysts with suspected endometrioma.

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