Publications by authors named "Yu-Ting Huang"
Charge density wave (CDW) is the phenomenon of a material that undergoes a spontaneous lattice distortion and modulation of the electron density. Typically, the formation of CDW is attributed to Fermi surface nesting or electron-phonon coupling, where the CDW vector (Q) corresponds to localized extreme points of electronic susceptibility or imaginary phonon frequencies. Here, we propose a new family of multiple CDW orders, including chiral Star-of-David configuration in nine 2D III-VI van der Waals materials, backed by first-principles calculations.
View Article and Find Full Text PDFObjective: To evaluate the safety and efficacy of partial splenic embolization (PSE) in treating chemotherapy-induced thrombocytopenia (CIT) in patients with colorectal cancer who failed to respond to platelet growth factor therapy.
Methods: 56 patients who underwent PSE were retrospectively analyzed. Based on the inclusion and the exclusion criteria, 29 patients were eligible for the study, of whom one underwent twice PSE procedures due to recurrent thrombocytopenia.
Tepotinib in Cholangiocarcinoma with MET Amplification: A Case Report.
Onco Targets Ther
October 2024
Cholangiocarcinoma is a malignant tumor that affects the bile ducts and is usually aggressive with poor prognosis. The treatment of cholangiocarcinoma depends on the stage and location of the tumor as well as the patient's overall health status. Systemic therapy, such as chemotherapy using gemcitabine and cisplatin, is the first choice for patients with cholangiocarcinoma who were inoperable.
View Article and Find Full Text PDFA significant complication of angiostrongyliasis remains eosinophilic meningoencephalitis, leading to patients' neurological deterioration, cerebral palsy, and respiratory changes, resulting in death. Clinically, A. cantonensis-infected patients sometimes showed decreased CSF glucose levels.
View Article and Find Full Text PDFObjectives: Laparoscopic hepatectomy (LH) for hepatocellular carcinoma (HCC) has been well known for its advantages in the past 10 years, but little is known regarding its oncologic outcomes while the technique is being developed at an institution. This study aimed to evaluate the safety and effectiveness of LH for patients with primary HCC at favorable locations, focusing on postoperative short- and long-term outcomes during the development period.
Materials And Methods: We retrospectively reviewed patients diagnosed with primary HCC who underwent hepatectomy between January 2013 and December 2019 at Hualien Tzu Chi Hospital.
Background: Previous studies have shown that the Gaming Disorder Test (GDT) and Gaming Disorder Scale for Adolescents (GADIS-A) have promising validity and reliability when assessing symptoms of gaming disorder among young adults. However, validity and reliability properties of the two scales have not been established among a Vietnamese population.
Objective: The present study translated the GDT and GADIS-A into Vietnamese and examined their factor structures, measurement invariance, convergent validity, concurrent validity, and divergent validity among university students.
Article Synopsis
- - An artificial autonomic nervous system (ANS) has been developed using a new type of organic photoelectrochemical transistor (OPECT), which can mimic the functions of real human nervous systems by switching between excitatory and inhibitory responses!* - The system can change its behavior based on light and the neurotransmitter acetylcholine (ACh), allowing it to replicate complex neural patterns and functions.* - This artificial ANS is designed to control artificial muscles and pupils, making it suitable for real-world applications and more compatible with biological systems than previous solid-state technologies.*
Proteasome inhibitors have been applied to anticancer therapy by accumulating toxic misfolded proteins. However, chemical inactivation of proteasome generates aggresome, a Vimentin cage-enclosed subcellular structure quarantining HDAC6-Dynein-transported misfolded proteins before the protein toxicants are degraded by autophagy. Hence, aggresome may attenuate proteasome inhibitor drug-induced cytotoxicity.
View Article and Find Full Text PDFArticle Synopsis
- Human angiostrongyliasis is a disease caused by eating larvae from a worm called Angiostrongylus cantonensis that affects the brain and eyes.
- Current treatments use a medicine called albendazole, but long-term use of another medicine, corticosteroids, can cause problems.
- In a study, researchers found that adding a natural compound called quercetin to albendazole helps improve symptoms and heal the brain better than using either one alone.
Article Synopsis
- Diabetic foot ulcers (DFUs) are serious complications of diabetes that can lead to severe health issues like amputation and even death, highlighting the need for effective diagnostic methods.
- Traditional diagnoses rely on doctors' visual assessments, which can be subjective and prone to errors, while existing quantitative methods are often tedious and complex.
- The paper introduces a new model called FARRNet, which uses advanced techniques like spatial-channel attention and data augmentation to automatically classify DFUs, achieving better accuracy than previous models in medical diagnostics.
Cellular and molecular biology of posttranslational modifications in cardiovascular disease.
Biomed Pharmacother
October 2024
Article Synopsis
- Cardiovascular disease (CVD) is the leading global cause of death, and while its underlying mechanisms are being studied, many aspects remain unclear, requiring further research.
- Recent advances in proteomics have helped identify important posttranslational modifications, such as succinylation and nitrosylation, which play crucial roles in processes like cell metabolism and oxidative stress related to CVD.
- The review highlights the potential treatments for CVD through histone deacetylase (HDAC) inhibitors and suggests new research avenues regarding the role of posttranslational modifications in the disease's pathogenesis.
Article Synopsis
- This study investigated how different doses of tissue plasminogen activator (tPA) influence treatment outcomes in patients undergoing mechanical thrombectomy (MT) for stroke, particularly looking at standard (within 6 hours) and extended (after 6 hours) treatment windows.
- It was found that in the standard window, patients receiving full-dose tPA had significantly better functional outcomes after 90 days compared to those receiving a reduced dose (49% vs 21%).
- Conversely, in the extended window, the dosage of tPA (full vs reduced) did not impact functional outcomes, suggesting that the timing of the treatment is more critical than the tPA dosage in these cases.
Article Synopsis
- - Mutations in the survival motor neuron gene cause spinal muscular atrophy, but advances in gene therapy are showing promise in replacing this missing protein and improving patient outcomes.! - A systematic review and meta-analysis of 78 pre-clinical studies in mouse models found that the timing of therapy delivery is crucial for achieving the best results in survival motor neuron-replacement therapies.! - The analysis revealed that these therapies improved survival rates, with a positive effect size of 1.20, highlighting the importance of early intervention for optimal efficacy.
Article Synopsis
- * The study used advanced techniques such as proteomics and interactomics on mouse models with varying disease severities to identify networks of proteins and their interactions that illuminate both similarities and differences in SMA presentation.
- * By integrating data on the SMN protein with these molecular networks, researchers were able to pinpoint critical connections and disruptions that contribute to SMA, offering a new way to analyze monogenic diseases through a systematic approach.
Article Synopsis
- Oxidative stress from cigarette smoke is linked to cellular dysfunction, particularly affecting mitochondrial function in skeletal muscles, especially in middle-aged mice.
- The study tested a mitochondria-targeted antioxidant, MitoTEMPO (MT), to see if it could counteract the damaging effects of cigarette smoke on muscle respiratory capacity.
- Results showed that while cigarette smoke reduced respiration in muscle fibers, MitoTEMPO partially restored some respiratory functions, suggesting that targeting mitochondrial oxidative stress could be a potential treatment for smoke-related impairments.
Direct copper-to-copper (Cu-Cu) bonding is a promising technology for advanced electronic packaging. Nanocrystalline (NC) Cu receives increasing attention due to its unique ability to promote grain growth across the bonding interface. However, achieving sufficient grain growth still requires a high thermal budget.
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- Dysphagia, common among elderly ICU patients, is linked to malnutrition, which can worsen outcomes like delirium and increase healthcare costs.
- The study aimed to examine how malnutrition relates to the occurrence of delirium in elderly dysphagic patients in the ICU, analyzing data from 2,273 patients aged 65 and older.
- The findings revealed that 13% of patients were malnourished, with a 55.9% incidence of delirium in this group, highlighting a strong association between malnutrition and higher rates of delirium (OR = 1.96).
Reproducing human visual functions with artificial devices is a long-standing goal of the neuromorphic domain. However, emulating the chemical language communication of the visual system in fluids remains a grand challenge. Here, a "multi-color" hydrogel-based photoelectrochemical retinomorphic synapse is reported with unique chemical-ionic-electrical signaling in an aqueous electrolyte that enables, e.
View Article and Find Full Text PDFBackground: Ultrasonography is used to diagnose carpal tunnel syndrome (CTS) according to various criteria. This diagnostic meta-analysis aimed to evaluate the efficacy of ultrasonography for diagnosing CTS, focusing on the cross-sectional area (CSA) of the median nerve (MN) at the inlet of the carpal tunnel and regional variations in diagnostic thresholds between Asian and non-Asian populations.
Methods: A comprehensive literature search was conducted using PubMed, Embase, and the Cochrane Library.
Background And Purpose: Parents of preterm infants experience anxiety and stress in the neonatal intensive care unit (NICU). Visitation restrictions due to COVID-19 have increased maternal pressure and limited bonding opportunities. Little research exists in Taiwan on using video conferencing as a solution.
View Article and Find Full Text PDFCandida albicans is a leading cause of intravascular catheter-related infections. The capacity for biofilm formation has been proposed to contribute to the persistence of this fungal pathogen on catheter surfaces. While efforts have been devoted to identifying microbial factors that modulate C.
View Article and Find Full Text PDFBackground: Critically ill neonates receive care in the neonatal intensive care unit (NICU). Unfortunately, some neonates pass away in the NICU. Providing comprehensive neonatal palliative care and hospice services is crucial in supporting parents through the loss of their offspring.
View Article and Find Full Text PDFBackground: Hemorrhagic transformation (HT) is a serious complication after endovascular thrombectomy (EVT) for patients with acute ischemic stroke (AIS). We analyzed the plasma levels of MMP-9 before and after EVT and assessed the temporal changes of MMP-9 that may be associated with, and therefore predict, HT after EVT.
Methods: We enrolled 30 AIS patients who received EVT, and 16 (53.