Publications by authors named "Yu-Ting Fu"
Health and well-being of maturing adults with classic galactosemia.
J Inherit Metab Dis
January 2025
Article Synopsis
- A study analyzed long-term health outcomes in 92 adults (ages 30-78) with classic galactosemia (CG) and 38 unaffected siblings (ages 30-79) using anonymous surveys covering various health domains.
- Results showed that long-term complications in areas such as cognition, motor function, and psychosocial well-being persisted similarly to reports from younger groups, suggesting these issues do not worsen with age for most CG patients.
- The study explored connections between health outcomes and factors like early diet restrictions and age, finding some links to cataracts and bone health, but no significant trends were observed overall.
Article Synopsis
- The study investigates immune persistence after switching from trivalent oral poliovirus vaccine (tOPV) to a new immunization schedule (IPV and bOPV) since 2016.
- Blood samples were collected from 1104 participants at various ages to measure antibody levels against polioviruses.
- Results showed that while type 1 and type 3 antibody rates were similar across groups, the 2-specific antibody rates were much higher in the IPV-IPV-tOPV group compared to others, indicating some schedules did not effectively maintain immunity against poliovirus type 2.
To provide a basis for further optimization of the polio sequential immunization schedule, this study evaluated the effectiveness of booster immunization with one dose of bivalent oral poliovirus vaccine (bOPV) at 48 months of age after different primary polio immunization schedules. At 48 months of age, one dose of bOPV was administered, and their poliovirus types 1-3 (PV1, PV2, and PV3, respectively)-specific neutralizing antibody levels were determined. Participants found to be negative for any type of PV-specific neutralizing antibody at 24, 36, or 48 months of age were re-vaccinated with inactivated polio vaccine (IPV).
View Article and Find Full Text PDFUrsolic acid (UA) exists in a variety of medicinal plants. UA exhibits antimicrobial activity against several microorganisms; however, little is known regarding the potential antifungal effect of UA on Cryptococcus neoformans (C. neoformans).
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