Publications by authors named "Yu-Tang Yang"

Background/aims: Ineffective esophageal motility (IEM) is common in patients with gastroesophageal reflux disease (GERD) and can be associated with poor esophageal contraction reserve on multiple rapid swallows. Alterations in the esophageal microbiome have been reported in GERD, but the relationship to presence or absence of contraction reserve in IEM patients has not been evaluated. We aim to investigate whether contraction reserve influences esophageal microbiome alterations in patients with GERD and IEM.

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Antibiotics used as growth promoters in livestock and animal husbandry can be detected in animal-derived food. Epidemiological studies have indicated that exposure to these antibiotic residues in food may be associated with childhood obesity. Herein, the effect of exposure to a residual dose of tylosin-an antibiotic growth promoter-on host metabolism and gut microbiota was explored .

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Article Synopsis
  • This study investigates the connection between gut microbiota and low muscle mass in older adults, revealing that those with low muscle mass (LM) have decreased gut microbiome diversity compared to those with normal muscle mass (NM).
  • It identifies specific changes in gut bacteria, such as a reduced Firmicutes/Bacteroidetes ratio and lower levels of butyrate-producing bacteria in the LM group, which correspond to a decrease in skeletal muscle mass.
  • The findings suggest that gut microbiome profiles and fecal butyrate levels could potentially be used as early indicators for diagnosing sarcopenia in the elderly.
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Cardiovascular disease (CVD) is strongly associated with the gut microbiota and its metabolites, including trimethylamine-N-oxide (TMAO), formed from metaorganismal metabolism of ʟ-carnitine. Raw garlic juice, with allicin as its primary compound, exhibits considerable effects on the gut microbiota. This study validated the benefits of raw garlic juice against CVD risk via modulation of the gut microbiota and its metabolites.

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