[Expression and significance of basic fibroblast growth factor and transforming growth factor-beta 1 in mucoepidermoid carcinoma with different malignant degree].

Objective: To study the expression and significance of basic fibroblast growth factor(bFGF)and transforming growth factor-beta 1 (TGF-beta1) in mucoepidermoid carcinomas with different malignant degree.

Methods: Using immunohistochemistry (IHC) staining technique, bFGF and TGF-beta1 proteins in the mucoepidermoid carcinoma tissues with different malignant degree, including well-differentiated, moderately differentiated and poorly differentiated mucoepidermoid carcinoma, and normal salivary gland tissue were detected.

Results: The positive rate of bFGF and TGF-beta1 in normal salivary glands were apparently lower than those in malignant mucoepidermoid carcinomas (P<0.

[Facial multiple malignant proliferating tricholemmoma: a case report].

Malignant proliferating tricholemmoma is a very rare dermatic annexal tumor originated from outer root sheath cells. In this article, a case of facial multiple malignant proliferating tricholemmoma was reported, and its clinical pathologic features, differential diagnosis, treatment methods and histogenesis were discussed by reviewing relevant literatures.

The expression profile of microRNAs in a model of 7,12-dimethyl-benz[a]anthrance-induced oral carcinogenesis in Syrian hamster.

Background: Non-coding RNA molecules, such as microRNAs, may play an important role in carcinogenesis. Recent studies have indicated that microRNAs are involved in initiation and progression of various malignancies. However, little work has been done to compare the microRNA expression patterns in oral cancer.

Correlation between the expression of thrombospondin-1 and neovascularization in mucoepidermoid carcinoma.

Background: Researchers have recently demonstrated that thrombospondin-1 (TSP-1) has an important function in regulating neovascularization. Whether it inhibits or accelerates neovascularization, however, is still controversial. We found few reports about the correlation between TSP-1 and vascularization in mucoepidermoid carcinoma.

[Correlation between the expression of thrombospondin-1 and the angiogenesis in mucoepidermoid carcinoma].

Objective: To study the relationship between the expression of thrombospondin-1 (TSP-1) and the angiogenesis in mucoepidermoid carcinoma.

Methods: Immunohistochemistry were applied to detect the expression of TSP-1 and the value of microvessel density (MVD) in 45 mucoepidermoid carcinoma patients.

Results: Positive expressions of TSP-1 protein were detected in 26 of the 45 (57.