Psychometric Properties of Chinese Version of the Barriers to Error Disclosure Assessment (C-BEDA) Tool.

Aim: The Barriers to Error Disclosure Assessment (BEDA) tool is used to measure barriers to the disclosure of medical errors by healthcare professionals. This study aimed to evaluate the psychometric properties of the Chinese version of the BEDA (C-BEDA).

Background: The culture of disclosure and transparency in response to medical errors has been recommended in recent years.

RETRACTED: Development and evaluation of a second victim training course for nursing managers.

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CCDC92 promotes podocyte injury by regulating PA28α/ABCA1/cholesterol efflux axis in type 2 diabetic mice.

Podocyte lipotoxicity mediated by impaired cellular cholesterol efflux plays a crucial role in the development of diabetic kidney disease (DKD), and the identification of potential therapeutic targets that regulate podocyte cholesterol homeostasis has clinical significance. Coiled-coil domain containing 92 (CCDC92) is a novel molecule related to metabolic disorders and insulin resistance. However, whether the expression level of CCDC92 is changed in kidney parenchymal cells and the role of CCDC92 in podocytes remain unclear.

[Effect of liposome on permeability and drug retention of sodium fluorescein in rat skin: an experimental study].

Objective: To investigate the effect of liposome on the permeability and drug retention of sodium fluorescein(NaFl) in rat skin.

Methods: With an improved Franz diffusion cell and 0.125% NaFl liposome suspension as the model drug, in vitro measurement of percutaneous absorption and skin reservoir capacity for NaF1 was conducted using a fluorescence spectrophotometry at 4 and 12 h respectively after the diffusion experiment had started, and distribution of the fluorescence in rat skin was observed under fluorescence microscope at 4 h penetration experiment.

Clinical analysis of 12 cases of pyoderma gangrenosum.

Twelve cases of pyoderma gangrenosum is reported in light of the clinical data including the patients' gender, age, complications, laboratory examinations, treatment and outcome, in an attempt to explore the pathogenesis, treatment and prognosis of the disease.

Experimental study of podophyllotoxin dipalmitoylphosphatidylcholine liposome for topical skin application.

Objective: To observe the drug release of podophyllotoxin liposome and the drug retention in the skin.

Methods: Two liposome suspensions containing respectively podophyllotoxin dipalmitoylphosphatidylcholine (DPPC) and soya bean lecithin were prepared ultrasonically. Podophyllotoxin anhydride and the liposome suspensions were applied onto the skin of young pigs to observe the drug retention in the skin at different time points in the following 2 days, with exclusive liposome or anhydride serving as control.

[Changes in serum concentration of podophyllotoxin after its topical application with liposome on rat skin].

Objective: To investigate the changes of serum concentration of podophyllotoxin after topical application of liposome podophyllotoxin suspension on rat skin.

Methods: SD rats were used in this study, which were divided into test group (n=48) to receive application of liposome podophyllotoxin (0.5 % ) suspension and control group (n=48) treated with 0.