Publications by authors named "Yu-Ru Shang"
To investigate if andrographolide impairs cholestatic liver injury. All rats were randomly divided into six groups-(1) control (n = 6), (2) control + 200 mg/kg andrographolide (n = 6), (3) alpha-naphthylisothiocyanate (ANIT)-control (n = 6), (4) ANIT + 50 mg/kg andrographolide (n = 6), (5) ANIT + 100 mg/kg andrographolide (n = 6), and (6) ANIT + 200 mg/kg andrographolide (n = 6). We gavaged 50 mg/kg ANIT to mimic cholestatic liver injury in rats.
View Article and Find Full Text PDFThe purpose of this present study is to prepare NF-κB/p65 antisense oligonucleotide loaded chitosan nanoparticles (NPs) and evaluate their physicochemical characterization and antisense effects in RAW264.7 macrophages. Condensed nanoparticles with mean particle size of 128±16nm, average Zeta potential of 19.
View Article and Find Full Text PDF[Structural and functional changes in islet beta cells in severely scalded rats].
Zhonghua Shao Shang Za Zhi
August 2013
Article Synopsis
- - The study aimed to investigate how severe burns affect islet beta cells and their role in glycometabolism in scalded rats.
- - Researchers divided 72 Wistar rats into two groups: one subjected to severe burns and the other to a sham treatment, then measured plasma glucose levels and analyzed pancreatic tissue for insulin and beta cell characteristics at various recovery stages.
- - Results showed that the burned rats had significantly higher glucose levels and glucose tolerance issues compared to the control group shortly after injury, but their glucose levels approached those of controls by day 7 post-injury.