Role of NGF in spared DRG following partial dorsal rhizotomy in cats.

Neuroplasticity occurs in the spinal cord in response to lesions, but less is known about the underlying mechanism. This investigation explored the role of intrinsic NGF in axonal sprouting of dorsal root ganglia (DRG) in cats subjected to unilateral removal of L1-L5, L7-S2 DRG, but leaving the L6 DRG (spared DRG) undamaged. The expression of mRNA and protein for NGF and TrkA increased significantly by using in situ hybridization histochemistry and immunohistochemistry.

[Effect of tetramethylpyrazine on the responses of respiration and expression of nNOS in brainstem to hypoxia in rats].

The aim of the present study was to investigate the effect of tetramethylpyrazine (TMP) on the changes of respiration and expression of neuronal nitric oxide synthase (nNOS) in brainstem induced by hypoxia in the rats. Hypoxia was induced by inhalation of 8% O2-balanced N2.The electromyogram (EMG) of diaphragm was monitored to evaluate the respiratory response of the rats to hypoxia.

[A study of the dynamic relationship between AVP mRNA expression in PVN and immuno-responsiveness in rats].

Objective: To investigate the proper dynamic relationship between AVP mRNA expression in PVN and immune response.

Methods: Through the establishment of the immuno-enhancement and immunosuppression rat models, the in situ hybridization histochemical methods and the images analytical techniques were used to detect the dynamic variations of AVP mRNA content of PVN during different periods of immune response.

Results: 1.