The complete mitochondrial genome for Stanley's slug snake (Serpentes: Pareidae) by next-generation sequencing.

The complete mitochondrial DNA (mtDNA) for was determined in this study. The length of complete mtDNA was 18,932 bp, including 13 protein-coding genes (PCGs) (, , , , and ), 23 tRNA genes, 2 rRNA genes, a L-chain replication-initiating non-coding region (NCR) and 2 control regions. The overall base composition of the sequence is 24.

Mutations of PQBP1 in Renpenning syndrome promote ubiquitin-mediated degradation of FMRP and cause synaptic dysfunction.

Renpenning syndrome is a group of X-linked intellectual disability syndromes caused by mutations in human polyglutamine-binding protein 1 (PQBP1) gene. Little is known about the molecular pathogenesis of the various mutations that cause the notable variability in patients. In this study, we examine the cellular and synaptic functions of the most common mutations found in the patients: c.