Publications by authors named "Yu-Ming Tsao"

Introduction: The early detection of esophageal cancer is crucial to enhancing patient survival rates, and endoscopy remains the gold standard for identifying esophageal neoplasms. Despite this fact, accurately diagnosing superficial esophageal neoplasms poses a challenge, even for seasoned endoscopists. Recent advancements in computer-aided diagnostic systems, empowered by artificial intelligence (AI), have shown promising results in elevating the diagnostic precision for early-stage esophageal cancer.

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  • The study explores hyperspectral imaging (HSI) as a method for detecting dementia by examining changes in the retina related to amyloid beta (Aβ) formations.
  • Utilizing a dataset of 3,256 images from participants aged 60 to 85, researchers found important changes in spectral reflection intensity, especially between 600 nm and 780 nm.
  • The findings suggest that HSI could serve as a non-invasive diagnostic tool for early dementia detection, emphasizing the need for further research into its effectiveness.
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This study utilizes spectral analysis to quantify water pollutants by analyzing the images of biological oxygen demand (BOD). In this study, a total of 2545 images depicting water quality pollution were generated due to the absence of a standardized water pollution detection method. A novel snap-shot hyperspectral imaging (HSI) conversion algorithm has been developed to conduct spectral analysis on traditional RGB images.

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  • Narrow-band imaging (NBI) is more effective at identifying early gastrointestinal cancer compared to traditional white light imaging (WLI), but NBI is not currently available in magnetic-assisted capsule endoscopy (MACE) due to technical limitations.
  • MACE is a patient-friendly alternative to conventional endoscopy, which raises the need to integrate NBI-like capabilities into MACE systems.
  • Researchers have developed a new image enhancement technique called Spectrum Aided Visual Enhancer (SAVE) that improves mucosal visualization in MACE, achieving a high similarity to NBI images, suggesting promising future applications.
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The early detection of esophageal cancer presents a substantial difficulty, which contributes to its status as a primary cause of cancer-related fatalities. This study used You Only Look Once (YOLO) frameworks, specifically YOLOv5 and YOLOv8, to predict and detect early-stage EC by using a dataset sourced from the Division of Gastroenterology and Hepatology, Ditmanson Medical Foundation, Chia-Yi Christian Hospital. The dataset comprised 2741 white-light images (WLI) and 2741 hyperspectral narrowband images (HSI-NBI).

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Esophageal carcinoma (EC) is a prominent contributor to cancer-related mortality since it lacks discernible features in its first phases. Multiple studies have shown that narrow-band imaging (NBI) has superior accuracy, sensitivity, and specificity in detecting EC compared to white light imaging (WLI). Thus, this study innovatively employs a color space linked to décor to transform WLIs into NBIs, offering a novel approach to enhance the detection capabilities of EC in its early stages.

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The clinical signs and symptoms of esophageal cancer (EC) are often not discernible until the intermediate or advanced phases. The detection of EC in advanced stages significantly decreases the survival rate to below 20%. This study conducts a comparative analysis of the efficacy of several imaging techniques, including white light image (WLI), narrowband imaging (NBI), cycle-consistent adversarial network simulated narrowband image (CNBI), and hyperspectral imaging simulated narrowband image (HNBI), in the early detection of esophageal cancer (EC).

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Video capsule endoscopy (VCE) is increasingly used to decrease discomfort among patients owing to its small size. However, VCE has a major drawback of not having narrow band imaging (NBI) functionality. The current VCE has the traditional white light imaging (WLI) only, which has poor performance in the computer-aided detection (CAD) of different types of cancer compared to NBI.

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One of the leading causes of cancer deaths is esophageal cancer (EC) because identifying it in early stage is challenging. Computer-aided diagnosis (CAD) could detect the early stages of EC have been developed in recent years. Therefore, in this study, complete meta-analysis of selected studies that only uses hyperspectral imaging to detect EC is evaluated in terms of their diagnostic test accuracy (DTA).

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Hydroxychloroquine, also known as quinine, is primarily utilized to manage various autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis, and Sjogren's syndrome. However, this drug has side effects, including diarrhea, blurred vision, headache, skin itching, poor appetite, and gastrointestinal discomfort. Blurred vision is caused by irreversible retinal damages and can only be mitigated by reducing hydroxychloroquine dosage or discontinuing the drug under a physician's supervision.

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The severity of diabetic retinopathy (DR) is directly correlated to changes in both the oxygen utilization rate of retinal tissue as well as the blood oxygen saturation of both arteries and veins. Therefore, the current stage of DR in a patient can be identified by analyzing the oxygen content in blood vessels through fundus images. This enables medical professionals to make accurate and prompt judgments regarding the patient's condition.

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In this study, we present the growth of monolayer MoS (molybdenum disulfide) film. Mo (molybdenum) film was formed on a sapphire substrate through e-beam evaporation, and triangular MoS film was grown by direct sulfurization. First, the growth of MoS was observed under an optical microscope.

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In this study, a snapshot-based hyperspectral imaging (HSI) algorithm that converts RGB images to HSI images is designed using the Raspberry Pi environment. A Windows-based Python application is also developed to control the Raspberry Pi camera and processor. The mean gray values (MGVs) of two distinct regions of interest (ROIs) are selected from three samples of 100 NTD Taiwanese currency notes and compared with three samples of counterfeit 100 NTD notes.

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Many studies have recently used several deep learning methods for detecting skin cancer. However, hyperspectral imaging (HSI) is a noninvasive optics system that can obtain wavelength information on the location of skin cancer lesions and requires further investigation. Hyperspectral technology can capture hundreds of narrow bands of the electromagnetic spectrum both within and outside the visible wavelength range as well as bands that enhance the distinction of image features.

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One of the challenges in differentiating a duplicate hologram from an original one is reflectivity. A slight change in lighting condition will completely change the reflection pattern exhibited by a hologram, and consequently, a standardized duplicate hologram detector has not yet been created. In this study, a portable and low-cost snapshot hyperspectral imaging (HSI) algorithm-based housing module for differentiating between original and duplicate holograms was proposed.

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Surface defect detection is a crucial step in ensuring the quality of lenses. One method to check for surface defects is to use an optical system integrated with an industrial camera to magnify and highlight the position of a defect on the surface of a lens. Therefore, automatic optical inspection systems are applied to detect micro-defects.

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Forgery and tampering continue to provide unnecessary economic burdens. Although new anti-forgery and counterfeiting technologies arise, they inadvertently lead to the sophistication of forgery techniques over time, to a point where detection is no longer viable without technological aid. Among the various optical techniques, one of the recently used techniques to detect counterfeit products is HSI, which captures a range of electromagnetic data.

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In this study, the combination of hyperspectral imaging (HSI) technology and band selection was coupled with color reproduction. The white-light images (WLIs) were simulated as narrow-band endoscopic images (NBIs). As a result, the blood vessel features in the endoscopic image became more noticeable, and the prediction performance was improved.

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Early detection of esophageal cancer has always been difficult, thereby reducing the overall five-year survival rate of patients. In this study, semantic segmentation was used to predict and label esophageal cancer in its early stages. U-Net was used as the basic artificial neural network along with Resnet to extract feature maps that will classify and predict the location of esophageal cancer.

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In this study, n-type MoS monolayer flakes are grown through chemical vapor deposition (CVD), and a p-type CuO thin film is grown via electrochemical deposition. The crystal structure of the grown MoS flakes is analyzed through transmission electron microscopy. The monolayer structure of the MoS flakes is verified with Raman spectroscopy, multiphoton excitation microscopy, atomic force microscopy, and photoluminescence (PL) measurements.

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Molybdenum disulfide (MoS) was grown on a laser-processed periodic-hole sapphire substrate through chemical vapor deposition. The main purpose was to investigate the mechanism of MoS growth in substrate with a periodic structure. By controlling the amount and position of the precursor, adjusting the growth temperature and time, and setting the flow rate of argon gas, MoS grew in the region of the periodic holes.

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  • Morganella morganii is a clinically significant enterobacterium linked to severe infections such as bacteraemia and sepsis, particularly in hospitalized patients, with a high mortality rate despite effective antibiotic treatment.
  • The KT strain genome of M. morganii was sequenced, revealing 3,565 protein-coding sequences, several pathogenicity-related genes, and unique features like the eut operon for ethanolamine metabolism and cobalamin biosynthesis.
  • Comparisons with other Enterobacteriaceae genomes showed distinct similarities in their systems, but noteworthy differences highlight M. morganii's unique genetic traits that contribute to its pathogenicity.
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  • Cardiovascular disease, particularly myocardial infarction (MI), is a leading cause of death in Taiwan, often linked to hyperlipidemia and atherosclerosis.
  • This study analyzed copy number variations (CNV) in blood samples from 31 MI patients with hyperlipidemia, identifying seven significant CNV regions associated with these conditions.
  • The findings suggest these CNV regions could serve as potential biomarkers for early diagnosis of hyperlipidemia and MI, offering new avenues for research.
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