Publications by authors named "Yu-Liang Qian"

Objective: Coronary heart disease (CHD) has been regarded as a serious and common disease in the modern society. This study aims to investigate the effect of Granule of BU-XIN RUAN-MAI (BXRM) on angina pectoris of coronary heart disease and to explore the molecular mechanisms underlying Granule of BU-XIN RUAN-MAI-mediated protective activity against this disease.

Methods: The effects of Granule of BU-XIN RUAN-MAI on clinical symptoms of patients' angina were indicated by hemorheology indicators including high shear of blood viscosity, low shear of blood viscosity, plasma viscosity, erythrocyte rigidity index, D-D dimer, fibrinogen content, and lipid content.

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Rationale: Atherosclerotic cardiovascular disease (ASCVD), including coronary heart disease (CHD), atherosclerotic stroke and peripheral vascular disease, has become the most deadly chronic noncommunicable disease throughout the world in recent decades, while plaque regression could reduce the occurrence of ASCVD. Traditional Chinese Medicine (TCM) has been widely used for prevention and treatment of these diseases. In the perspective of TCM, phlegm and blood stasis are considered to be leading pathogenesis for CHD.

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Rationale: Sinus bradycardia refers to a sinus heart rate <60 bpm. Cardiac sinus arrests refer to the omission of atrial activation caused by transient cessation of impulse generation at the sinoatrial node. Normally, drugs such as atropine, isoproterenol, dopamine, dobutamine, or epinephrine can be used for the acute treatment of bradycardia.

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Synopsis of recent research by authors named "Yu-Liang Qian"

  • - Yu-Liang Qian's research primarily focuses on the therapeutic effects of Traditional Chinese Medicine (TCM) in treating cardiovascular diseases, particularly emphasizing conditions like coronary heart disease (CHD) and its associated symptoms, such as angina pectoris.
  • - Recent studies demonstrate the positive effects of Granule of BU-XIN RUAN-MAI in mitigating angina pectoris by regulating specific molecular signaling pathways, showcasing a blend of traditional and modern medical approaches.
  • - Other significant contributions include exploring the management of lipid-lowering therapies in patients with severe liver dysfunction and the application of TCM in treating cardiac arrhythmias like sinus bradycardia, thereby highlighting TCM's potential in complex clinical scenarios.