Publications by authors named "Yu-Kwang Lee"
Article Synopsis
- Thyroid cancer rates have risen significantly among Taiwanese females, with age-adjusted rates increasing from 7.37 to 20.53 per 100,000 people between 1995-1999 and 2015-2019, respectively.
- The study found younger females showed the highest increase in incidence rates, particularly in the 50-54 age group, with a notable trend linked to later birth cohorts.
- Researchers suggested that overdiagnosis might largely explain this trend, alongside a significant negative correlation between thyroid cancer incidence and fertility rates, highlighting a need for further investigation into these relationships.
Although male breast cancer (MBC) is globally rare, its incidence significantly increased from 1990 to 2017. The aim of this study was to examine variations in the trends of MBC incidence between populations in Taiwan and the USA from 1980 to 2019. The Taiwan Cancer Registry database and the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute of the USA were used.
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- Taiwan has one of the highest rates of upper tract urothelial cancer (UTUC) in the world, especially among women, but there has been no comprehensive long-term study on this issue.
- A nationwide analysis of UTUC incidence from 1985 to 2019 used data from the Taiwan Cancer Registry, breaking down the population into nine age groups to assess age-specific trends.
- The findings revealed a notable increase in renal pelvis cancer incidence, with women experiencing a higher rise than men, particularly in older age groups and among younger cohorts compared to older ones.
Article Synopsis
- In Taiwan, high rates of cigarette smoking, betel chewing, and alcohol consumption have led to significant cancer deaths, particularly in the oral cavity and throat.
- Analysis from 1980 to 2019 showed strong links between these cancers and lifestyle factors, with a notable period effect from 1990 to 2009 related to betel nut consumption and an ongoing effect from HPV on oropharyngeal cancers.
- Government initiatives to reduce smoking and betel quid usage since the 1990s have successfully stabilized cancer rates, suggesting continued policy impact may lead to further declines in head and neck cancer incidence.
In Taiwan, the age-standardized incidence of EC, especially esophageal squamous cell carcinoma (ESCC), has increased substantially during the past thirty years. We described the incidence trends of EC from 1985−2019 by an average annual percentage change (AAPC) and age-period-cohort model by using Taiwan Cancer Registry data. Age-period-cohort modeling was used to estimate the period and cohort effects of ESCC and esophageal adenocarcinoma (EAC).
View Article and Find Full Text PDFBackground: Intrahepatic cholangiocarcinoma (ICC) is one of the most aggressive malignancies. However, because of its scarcity there are limited population-based data available for investigations into its epidemiologic characteristics. In Taiwan, we have a national cancer registry database that can be used to evaluate the secular trends of ICC.
View Article and Find Full Text PDFMinimally invasive esophagectomy has gradually been accepted as an active treatment option for surgery of esophageal cancer. However, there is no consensus about how to perform the procedures in the thoracic and abdominal phase including anastomosis in the neck (McKeown) or chest (Ivor Lewis), VATS, robotic-assisted or reduced port approaches or various endoscopic abrasion techniques. Further studies to investigate the roles of these novel techniques are required to treat the various patient populations.
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