Publications by authors named "Yu-Ke Jiang"
Article Synopsis
- - A study analyzed 566 patients with early-stage nasopharyngeal carcinoma (NPC) from 2004 to 2019 to identify independent risk factors linked to the disease.
- - Older age groups, specifically those aged 70-79 and over 80, were found to significantly increase risks of mortality, with hazard ratios indicating higher danger compared to younger patients.
- - Additionally, Asian and Pacific Islander residents had a lower risk of developing early-stage NPC compared to White residents, and smaller tumor sizes (<3 cm) provided better survival rates overall.
Front Pharmacol
December 2022
Article Synopsis
- Ecto-5'-nucleotidase (NT5E), which encodes CD73, is linked to a tumor microenvironment that suppresses immune responses, leading to worse patient outcomes and increased cancer metastasis and treatment resistance.
- The study analyzed NT5E expression across various cancers, finding that higher levels correlate with poor overall survival in specific cancers, including pancreatic and stomach cancers.
- Additionally, NT5E was associated with increased infiltration of certain immune cells, like cancer-associated fibroblasts, indicating its significant role in tumor progression and the immune landscape.
