Publications by authors named "Yu-Jun Long"
Article Synopsis
- The document serves to correct an earlier published article identified by DOI: 10.3389/fpsyt.2021.638773.
- It updates specific information or errors found in the original publication.
- The correction aims to enhance the clarity and accuracy of the findings presented in the original study.*
Article Synopsis
- The review focuses on understanding the causes of negative symptoms and cognitive dysfunction in schizophrenia, highlighting the roles of genetics and epigenetics.
- It discusses new treatments, including novel medications and advanced therapies like transcranial magnetic stimulation, aimed at alleviating these symptoms.
- The overall goal is to enhance treatment strategies for schizophrenia, improving outcomes for patients dealing with these challenges.
Schizophrenia is a severe mental disease which characterized by positive symptom, negative symptom, general pathology syndrome and cognitive deficits. In recent years, many studies have investigated the relationship between cognitive deficits and clinical characteristics in schizophrenia, but relatively few studies have been performed on first-episode drug-naïve patients. Eighty seven first-episode drug-naïve schizophrenia patients were assessed for positive symptom, negative symptom, general pathology symptom and cognitive deficits from the Positive and Negative Symptom Scale and MATRICS Consensus Cognitive Battery.
View Article and Find Full Text PDFArticle Synopsis
- Cognitive impairment is a major symptom of schizophrenia and is linked to the disorder's prognosis, with recent studies suggesting a possible connection between metabolic disorders and cognitive issues.
- The study involved 172 early-stage schizophrenia patients and assessed their metabolic parameters and cognitive function through the MATRICS Consensus Cognitive Battery (MCCB).
- Despite a high prevalence of cognitive impairment (84.7%) in this group, the analysis indicated no clear association between metabolic disorders and cognitive impairment, implying that other factors may be at play.
Unlabelled: Weight gain and metabolic disturbances, potentially influenced by increased appetite, are common effects of olanzapine treatment in patients with schizophrenia. In this study, we explored the association between olanzapine-induced weight gain and metabolic effects with increased appetite. Drug-naïve, first-episode schizophrenia patients were treated with olanzapine for 12 weeks.
View Article and Find Full Text PDFObjective: To explore clinical effect of external application of No.II prescription on preoperative detumescence for the treatment of calcaneal fracture through tarsal sinus approach.
Methods: From November 2016 to June 2018, 67 patients with calcaneal fracture were divided into control group(32 patients with ice compress) and research group(35 patients with external application of No.
In this study, the 3'untranslated region (3'UTR) of MHC class I chain-related gene A (MICA) were investigated in 104 healthy, unrelated Han individuals recruited from northern China, using PCR-sequencing method. Nine polymorphic sites were detected, which were in very strong linkage disequilibrium with each other .Seven different MICA 3'UTR alleles were identified, among which UTR1 predominated (0.
View Article and Find Full Text PDF1071-bp fragment was obtained from the Schistosoma japonicum (Chinese strain) adult cDNA library after the 3' and 5' ends of the incomplete expression sequence tag (EST) of succinate dehydrogenase iron-sulfur protein of Schistosoma japonicum (SjSDISP) were amplified by the anchored PCR with 2 pairs of primers designed according to the EST of SjSDISP and the sequence of multiclone sites of the library vector. Sequence analysis indicated that the fragment was a full-length cDNA with a complete open reading frame (ORF), encoding 278 amino acid residues. The fragment was cloned into prokaryotic expression vector pQE30, and subsequently sequenced and expressed in Escherichia coli.
View Article and Find Full Text PDF[Cloning and expression of the succinate dehydrogenase iron-sulfur protein of Schistosoma japonicum Chinese strain in E. coli].
Zhong Nan Da Xue Xue Bao Yi Xue Ban
August 2006
Objective: To clone the full-length gene encoding succinate dehydrogenase iron-sulfur protein of Schistosoma japonicum (SjSDISP) Chinese strain and express it in Escherichia coli.
Methods: According to the published incomplete EST (BU804141) of SjSDISP and the sequence of multiclone sites of lambda gt11 vector, 2 pairs of primers were designed and synthesized. Then the 3' and 5'ends of the EST of the SjSDISP from adult Schistosoma japonicum cDNA library were amplified by anchored PCR.
[Etiology of infectious diseases in the central nervous system].
Hunan Yi Ke Da Xue Xue Bao
August 2003
Objective: To determine the etiological characteristics of infectious diseases in the central neural system (CNS).
Methods: The serum and cerebral spinal fluid of acute patients in the CNS were detected for virus-specific IgM, IgG and pathogens with enzyme-linked immunosorbent assay as well as traditional bacterial and fungal culture.
Results: Of the 823 patients, 126 (15.
[Hela cells secrete interleukin-8 and interleukin-10 response to Chlamydia trachomatis entry].
Hunan Yi Ke Da Xue Xue Bao
April 2003
Objective: To investigate the effect of Chlamydia trachomatis serotype K infection on productions of IL-8 and IL-10 in supernatant of cultured Hela cells.
Methods: The levels of IL-8 and IL-10 productions were detected by cell culture method and ELISA assay.
Results: The amount of IL-8 and IL-10 in the cell culture supernatant rose with the increasing doses of Chlamydia trachomatis.