Publications by authors named "Yu-Jin Dong"
Article Synopsis
- Circular RNAs (circRNAs) are important non-coding RNAs linked to various diseases, especially cancers, but their roles in cervical cancer are not well understood.
- Recent studies identified 45 circRNAs significantly expressed in cervical cancer tissues, with hsa_circ_0018289 showing a notable increase in expression compared to normal tissues.
- Further experiments revealed that hsa_circ_0018289 contributes to cervical cancer cell growth and spread by acting as a "sponge" for miR-497, highlighting its potential role in promoting tumor development.
Article Synopsis
- ACP5 is crucial for bone resorption and osteoclast differentiation, and this study examines its role in lung adenocarcinoma (AD).
- The research found that ACP5 is often upregulated in lung AD tissues and its high expression correlates with worse overall survival and advanced disease stages.
- The results indicate that ACP5 could be a valuable prognostic biomarker for assessing tumor progression in lung adenocarcinoma patients.
Article Synopsis
- Emerging evidence indicates that the long noncoding RNA PVT1 is linked to the development of cervical cancer, with its levels found to be increased in affected tissues and cell lines.
- The study demonstrated that reducing PVT1 via siRNA led to significant decreases in cancer cell proliferation, migration, and invasion.
- Additionally, miR-424 was shown to be downregulated in cervical cancer, and PVT1 appears to inhibit miR-424, suggesting that PVT1 functions as a competing endogenous RNA (ceRNA), highlighting a potential new target for cervical cancer therapy.
