Publications by authors named "Yu-Jie Zhai"
Background: With the development of radiological technologies, radiotherapy has been gradually widely used in the clinic to intracranial tumours and become standardised. However, the related central nervous system disorders are still the most obvious complications after radiotherapy. This study aims to quantify the effectiveness of anlotinib, a small molecule inhibitor of multiple receptor tyrosine kinases, in mitigating acute phase of radiation-induced brain injury (RBI) in a mouse model.
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- - The study investigated the effectiveness of post-operative chemoradiotherapy in 30 patients with completely resected gastric cancer after D2 lymphadenectomy, highlighting ongoing debates about optimal treatment options.
- - Patients received a combination of chemotherapy and radiotherapy, with a specific regimen involving oxaliplatin, folinic acid, and 5-fluorouracil, administered in cycles over several weeks.
- - Results showed a relapse rate of 33.3% among patients, while the three-year overall survival rate was 72.7% and disease-free survival rate was 65%, indicating that this treatment approach is feasible for a significant number of patients.