The art of biodegradable polymer design for the treatments against osteomyelitis.

Osteomyelitis arises from the incomplete treatment of the external wounds in the healing process, while bacterial infections persist within the bone marrow, leading to abscess formation. Osteomyelitis treatments generally involve three main aspects: rapid bactericidal action, sustained bacteriostasis, and induction of bone regeneration. However, current treatment methods, which often combine surgical debridement with long-term high-dose intravenous antibiotic administration or poly(methyl methacrylate) (PMMA) beads antibiotic therapy, suffer from significant drawbacks and limitations.

Latent profiles of multi-dimensional sleep characteristics and association with overweight/obesity in Chinese preschool children.

Objectives: To examine the association between latent profiles of multi-dimensional sleep characteristics and overweight/obesity (OWO) in Chinese preschool children.

Study Design: The cross-sectional analysis included 3204 preschool children recruited from 24 kindergartens in Shanghai. Parents reported children's demographics and sleep characteristics, including sleep duration, timing and disturbances.

The complete chloroplast genome of Eastern Asian fern (Dryopteridaceae).

is a potential ornamental plant, which is restricted to eastern Asia. Here, we sequenced the complete chloroplast (cp) genome of and constructed a phylogenetic cp tree of Dryopteridaceae to study their relationships. The cp genome of is 153,093 bp in length, being made up of large single-copy (LSC, 83,169 bp), small single-copy (SSC, 21,538 bp), and a pair of region inverted repeats (IRs, 24,193 bp).

The application of a high-density street-level air temperature observation network (HiSAN): The relationship between air temperature, urban development, and geographic features.

The urban heat island effect in cities has become an important problem in relation to not only urban climate but also public health and urban planning. Tainan, which located in Southern Taiwan, is a compact city with intense development. Therefore, this study investigated the urban thermal condition by employing a high-density street-level air temperature observation network (HiSAN).

Effects of Cyclosporine A on the Development of Metanephros in the Pregnant BALB/c Mice.

Background:: Cyclosporine A (CsA) is a commonly used clinical immunosuppressant. However, CsA exposure in rabbits during the gestation period was shown to cause a postnatal decrease in the number of nephrons, with the effects remaining unknown. In this study, we aimed to explore the effects of CsA on metanephros development in the pregnant BALB/c mice.

[The safety and efficacy of regional citrate anticoagulation in sustained low efficiency dialysis].

Objective: To evaluate the safety and efficacy of regional citrate anticoagulation in sustained low efficiency dialysis (SLED).

Methods: A total of 45 patients with acute kidney injury (AKI) or end stage renal disease (ESRD) admitted in our hospital from August 2011 to September 2012 were prospectively enrolled in this study. All the patients received SLED treatment by Fresenius 4008sARrTplus dialyzer through either femoral or internal jugular venous catheter, with each session of SLED treatment lasting for 8 hours.

Citrate versus unfractionated heparin for anticoagulation in continuous renal replacement therapy.

Background: Unfractionated heparin is the most commonly used anticoagulant in continuous renal replacement therapy (CRRT), but it can increase the risk of bleeding. Citrate is a promising substitute. Our study was to assess the efficacy and safety of citrate versus unfractionated heparin in CRRT.