Publications by authors named "Yu-Jie Ke"

Article Synopsis
  • The basic helix-loop-helix (bHLH) transcription factors are important proteins found in many organisms that help regulate various biological processes, but they hadn't been comprehensively studied in orchids before this research.
  • In this study, 94 bHLH transcription factors were identified in orchids, divided into 18 subfamilies, with many linked to stress responses and hormone activities.
  • Analysis of gene expression revealed that 84 of these factors were expressed differently in sepals of various colors, suggesting their potential role in flower color through anthocyanin regulation, especially in specific bHLH subfamily genes.
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Article Synopsis
  • * A total of 136 CeMYB transcription factors were identified, categorized into various classes, and organized into 20 phylogenetic clusters, suggesting their diverse biological functions.
  • * Analyses showed that these CeMYBs are mostly located in the nucleus, contain stress-responsive elements, and may play a key role in flower color variation, providing insights for further research on anthocyanin biosynthesis.
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The marvelously diverse Orchidaceae constitutes the largest family of angiosperms. The genus Cymbidium in Orchidaceae is well known for its unique vegetation, floral morphology, and flower scent traits. Here, a chromosome-scale assembly of the genome of Cymbidium ensifolium (Jianlan) is presented.

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Migraine is one of the most common and highest burdens of disease. As a primary cerebral dysfunction illness, migraine might exhibit other system-related symptoms, including vestibular and cochlear symptoms. With the publication of the diagnostic criteria of vestibular migraine, the link between migraine and vestibular symptoms became clear.

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Peroxisome proliferator-activated receptor alpha/gamma (PPARα/γ) agonists have emerged as important pharmacological agents for improving insulin action. Propane-2-sulfonic acid octadec-9-enyl-amide (N15) is a novel PPARα/γ dual agonist synthesized in our laboratory. The present study investigates the efficacy and safety of N15 on insulin resistance regulation in high fat diet (HFD)-and streptozotocin (STZ)-induced diabetic mice and in palmitic acid (PA)-induced HepG2 cells.

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