Publications by authors named "Yu-Jia Hou"
Background: Small cell lung cancer (SCLC) is a common and aggressive subtype of lung cancer. It is characterized by rapid growth and a high mortality rate. Approximately 10% of patients with SCLC present with brain metastases at the time of diagnosis, which is associated with a median survival of 5 mo.
View Article and Find Full Text PDFArticle Synopsis
- Immune checkpoint inhibitors like PD-L1 and PD-1 have gained approval for treating advanced urothelial carcinoma (UC), but some patients may experience rapid tumor growth instead of improvement from these therapies.
- A case involving a 73-year-old woman with bladder UC showed that after receiving the anti-PD-L1 drug toripalimab and albumin-bound paclitaxel, her cancer progressed rapidly within two months, worsening her condition significantly.
- There’s a pressing need to identify patients who are likely to respond to immunotherapy, especially in older patients who have limited chemotherapy options; more research is necessary to understand the phenomenon of hyperprogression in these cases.
[Responses of Jatropha curcas L. seedlings to drought stress].
Ying Yong Sheng Tai Xue Bao
July 2008
By adding different concentrations (5%-25%) of polyethylene glycol (PEG) into Hoagland solution to simulate a gradient of drought stress, the photosynthetic characteristics and drought resistance of Jatropha curcas L. seedlings were investigated. The results showed that when treated with lower concentrations (< or = 15%) of PEG, the photosynthetic rate (Pn), stomatal conductance (Gs), and intercellular carbon dioxide concentration (Ci) of the seedlings decreased with increasing PEG concentration, while the chlorophyll fluorescence parameters optimal/maximal quantum yield of PS II (Fv/Fm) decreased slightly and minimal fluorescence (Fo) was almost unaltered.
View Article and Find Full Text PDF