The relationship between smoking and rosacea: A Mendelian randomization study.

Background: Rosacea can be seen in many patients nowadays, and the related causes are complex. Despite a certain association between smoking and rosacea being reported by several studies, the actual causality has not been established for the possible bias and confounders.

Methods: We used Mendelian randomization (MR) to evaluate a potential causal effect of smoking on rosacea risk.

Changes of Facial Lipidomics by Intense Pulsed Light Treatment Based on LC-MS.

Background: Intense pulsed light (IPL) has been widely used to improve cutaneous photoaging in recent years. Several studies began to explore the changes of skin barrier function after treatment, but the changes of skin surface lipids (SSL), especially specific lipid content and types are still unclear.

Methods: A total of 25 female volunteers were included in our study, and each of them received three full-face treatments with one month apart.

Microbial community structure is stratified at the millimeter-scale across the soil-water interface.

Soil-water interfaces (SWI) are biogeochemical hotspots characterized by millimeter-scale redox gradients, indicating that parallel changes are also present in microbial community structure and activity. However, soil-based analyses of microbial community structure typically examine bulk samples and seldom consider variation at a scale relevant to changes in environmental conditions. Here we presented a study that aimed to describe millimeter-scale variance in both microbial community structure and physicochemical properties in a lab flooded soil.

Reciprocal Substitution Between Methamphetamine and Heroin in Terms of Reinforcement Effects in Rats.

Heroin and methamphetamine are both popular illicit drugs in China. Previous clinical data showed that habitual users of either heroin or methamphetamine abuse the other drug for substitution in case of unavailability of their preferred drug. The present study aimed to observe whether heroin can substitute the methamphetamine reinforcement effect in rats, and vice versa.