Publications by authors named "Yu-Ji Chen"

Article Synopsis
  • Sixty-six MADS-box genes were identified in the Coptis teeta genome, primarily categorized into type I and type II, with most being type I.
  • Four pairs of gene duplications were found, indicating these genes may have been conserved through evolution, as suggested by low Ka/Ks ratios.
  • Differential expression of 38 MADS-box genes was observed between male and female floral phenotypes, providing new insights into floral development mechanisms in this medicinal plant.
View Article and Find Full Text PDF
Article Synopsis
  • The heat shock protein 70 (HSP70) family is critical in helping plants respond to abiotic stresses, but the specific mechanisms in Fritillaria cirrhosa under high temperature stress are not well understood.
  • Researchers identified 26 distinct HSP70 proteins in F. cirrhosa, which varied in length, weight, and structural features, and predicted their localization in key cell organelles.
  • The study found that certain HSP70 genes were significantly up-regulated at high temperatures, particularly in stems and leaves, suggesting important roles in the plant's heat stress response.
View Article and Find Full Text PDF
Article Synopsis
  • - C2H2-zinc finger transcription factors are a major gene superfamily crucial for regulating flowering, but their functions are not well understood in certain plants that exhibit specific floral traits.
  • - A genome-wide analysis identified 95 members of this gene family, revealing their distribution across chromosomes, evolutionary history, and potential roles in regulating phytohormones.
  • - Expression studies comparing two floral phenotypes indicated that specific C2H2-ZFP genes are differentially expressed, laying groundwork for future research on their role in floral development.
View Article and Find Full Text PDF

Hepatocellular carcinoma (HCC) often occurs following chronic hepatitis B virus (HBV) infection, leading to high recurrence and a low 5-year survival rate. We developed an overall survival (OS) prediction model based on protein expression profiles in HBV-infected nontumor liver tissues. We aimed to demonstrate the feasibility of using protein expression profiles in nontumor liver tissues for survival prediction.

View Article and Find Full Text PDF

Splicing factors (SFs) have been increasingly documented to perturb the genome of cancers. However, little is known about the alterations of SFs in hepatocellular carcinoma (HCC). This study comprehensively delineated the genomic and epigenomic characteristics of 404 SFs in HCC based on the multi-omics data from the Cancer Genome Atlas database.

View Article and Find Full Text PDF

Background: Previous studies have shown that miR-144-3p might be a potential biomarker in non-small cell lung cancer (NSCLC). Nevertheless, the comprehensive mechanism behind the effects of miR-144-3p on the origin, differentiation, and apoptosis of NSCLC, as well as the relationship between miR-144-3p and clinical parameters, has been rarely reported.

Methods: We investigated the correlations between miR-144-3p expression and clinical characteristics through data collected from Gene Expression Omnibus (GEO) microarrays, the relevant literature, The Cancer Genome Atlas (TCGA), and real-time quantitative real-time PCR (RT-qPCR) analyses to determine the clinical role of miR-144-3p in NSCLC.

View Article and Find Full Text PDF

Background: Hemodialysis dependence is an independent risk factor for hematogenous complication, including distant metastatic infection and osteomyelitis. Chronic osteomyelitis is a serious disease that fails to respond to aggressive medical and surgical treatment. Hyperbaric oxygen therapy has been proved to enhance bone and soft tissue healing in many studies.

View Article and Find Full Text PDF