Ablative Radiotherapy Reprograms the Tumor Microenvironment of a Pancreatic Tumor in Favoring the Immune Checkpoint Blockade Therapy.

The low overall survival rate of patients with pancreatic cancer has driven research to seek a new therapeutic protocol. Radiotherapy (RT) is frequently an option in the neoadjuvant or palliative settings for pancreatic cancer treatment. This study explored the effect of RT protocols on the tumor microenvironment (TME) and their consequent impact on anti-programmed cell death ligand-1 (PD-L1) therapy.

Assessing the environmental impact of five Pd-based catalytic technologies in removing of nitrates.

Emerging technologies involving chemical catalytic processes to remove nitrate from water have proven efficient and cost-effective. However, the environmental impact of noble metals and metals at the nanoscale used in these processes has become a topic of serious concern. The aim of this research was to develop a system for evaluating the environmental impact of technologies associated with Pd-based catalytic denitrification.