Publications by authors named "Yu-Hong Cao"

Background: Allergic cutaneous vasculitis (ACV) is a difficult disease to treat. At present, there is no effective treatment for this condition. Traditionally, immunosuppressants and hormones have been primarily used in its management, but the treatment effect is suboptimal, and it has several side effects.

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In the present paper, the Mn-doped ZnS quantum dots were synthesized in water, and the MPA was used as the stabilizer. Utilizing the strong quenching effect of Hg2+ to the phosphorescence of the ZnS: Mn quantum dots, the method to detect micro-quantity Hg2+ in water was established by using the quantum dots as the phosphorescence probes. Compared to the fluorescence methods, the phosphorescence has longer lifetime and higher selectivity, and avoids the interference of the fluorescence and the scattering light.

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Objective: To investigate the clinical and pathological features of progressive muscular dystrophy (PMD) in children and to provide help for the early and accurate diagnosis of PMD.

Methods: Retrospective analysis was performed on the clinical data of 99 hospitalized children with PMD, including clinical manifestations, age of onset, family history, creatase, electromyogram (EMG) and pathological changes of muscles.

Results: Of the 99 children with PMD, the age of onset was 0.

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The surface modified quantum dots (QDs) as fluorescence probe to quantitatively detect the Pb2+ in water phase was studied in the paper. Using the mercaptopropionic acid (MPA) as the stabilizer, the CdTe quantum dots were synthesized in water phase. Based on the quenching effect of the Pb2+ on the QDs fluorescence, the method for detecting trace Pb2+ using QDs as probe was established.

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Objective: To investigate the main inhalant allergens and their distribution patterns in children with allergic diseases from Xi'an and the surrounding area and to provide evidence for the prevention and treatment of allergic diseases in children.

Methods: Skin prick test was performed using liquid with 13 standardized allergens (ALK-ABELL, Denmark) on 3085 children from Xi'an and the surrounding area who were treated for allergic diseases between July 2006 and July 2011, to detect inhalant allergens.

Results: Of the 3085 patients, 1368 (44.

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Aim: To construct the prokaryotic fusion expression vector of human beta defensin 4 (HBD4), and to express GST-HBD4 fusion protein in Escherichia coli (E.coli) and prepare polyclonal antibody of GST-HBD4.

Methods: The gene encoding mature peptide of HBD4 (mHBD4) was amplified by PCR from cloning vector PMD18-T/HBD4 which contained the full-length HBD4 cDNA and then cloned into prokaryotic expression vector PGEX-4T-2 to construct PGEX-4T-2/mHBD4.

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Octa-carboxylic phthalocyanine aluminium (AlPc(COOH)8) was used as fluorescent probe of infrared region. The interaction of octa-carboxylic phthalocyanine aluminium (AlPc(COOH)s) and bovine serum albumin(BSA) was studied by UV/ Vis and fluorescence spectra methods. The binding constant KA and n of phthalocyanine aluminium with BSA were determined.

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Objective: To investigate the effects of curcumin (Cur) and erythromycin (EM) on multidrug resistance (MDR) reversal of K562/A02 cell line and their mechanism.

Methods: MTT assay was employed to determine the sensitivity of Cur, EM-treated K562/A02 cells to adriamycin (ADM). Flow cytometry was used to measure intracellular mean fluorescence intensity (MFI) of daunorubicin (DNR).

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Article Synopsis
  • The study aimed to examine how NMDAR expression changes in the hippocampal CA(1) region after hypoxic-ischemic brain damage (HIBD) in neonatal rats.
  • An experimental model of HIBD was created, and researchers used immunohistochemical staining and in situ hybridization to assess NMDAR expression in both normal and damaged brains.
  • Findings showed a slight decrease in NR1(+) cells at 2 hours post-injury, with numbers increasing significantly from 24 to 72 hours after HIBD, indicating that NMDAR expression is up-regulated following brain injury in neonatal rats.
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Objective: Human Parvovirus B19 (HPV B19) is a small (23 nm), non-enveloped DNA virus found in 1974. It has been proved that HPV B19 is associated with a variety of childhood diseases, such as erythema infectious, transient aplastic crisis, aplastic anemia, idiopathic thrombocytopenic purpura and arthropathy, etc. There have been no any effective vaccines to prevent HPV B19 infection so far.

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