Using a Veto paradigm to investigate the decision models in explaining Libet-style experiments.

The question of whether free will exists or not has intrigued philosophers for centuries. About 40 years ago, cognitive neuroscientists such as Benjamin Libet have joined the discussion by demonstrating that an ERP component, the readiness potential (RP), precedes the reported time of decision to act by a few hundred milliseconds. Libet et al.

Full-form vs. combinatorial processing of Chinese compound words: Evidence from mismatch negativity.

This study examined whether Chinese spoken compound words are processed via full-form access or combination through morphemes by recording mismatch negativity (MMN). MMN has been shown to be larger for linguistic units that involves full-form access (lexical MMN enhancement) and smaller for separate but combinable units (combinatorial MMN reduction). Chinse compound words were compared against pseudocompounds, which do not have full-form representations in the long-term memory and are "illegal" combinations.

Fronto-occipital mismatch responses in pre-attentive detection of visual changes: Implication on a generic brain network underlying Mismatch Negativity (MMN).

Current theories of pre-attentive change detection suggest a regularity or prediction violation mechanism involving a frontotemporal network. Modulations of the early inferior frontal cortex (IFC) mismatch response representing the effort in comparing a stimulus to the prediction, the superior temporal cortex (STC) response indicating deviance detection, and the late IFC response representing prediction model updating were consistently demonstrated in auditory change detection using event-related optical signal (EROS). If the prediction violation hypothesis is universal, a generic neural mechanism should be found in all sensory modalities.

The critical role of the inferior frontal cortex in establishing a prediction model for generating subsequent mismatch negativity (MMN): A TMS-EEG study.

Background: The prediction violation account of automatic or pre-attentive change detection assumed that the inferior frontal cortex (IFC) is involved in establishing a prediction model for detecting unexpected changes. Evidence supporting the IFC's contribution to prediction model is mainly based on the Mismatch Negativity (MMN) to deviants violating predictions that are established based on the frequently presented standard events. However, deviant detection involves processes, such as events comparison, other than prediction model establishment.

Functional connectivity of the frontotemporal network in preattentive detection of abstract changes: Perturbs and observes with transcranial magnetic stimulation and event-related optical signal.

Current theories of automatic or preattentive change detection suggest a regularity or prediction violation mechanism involving functional connectivity between the inferior frontal cortex (IFC) and the superior temporal cortex (STC). By disrupting the IFC function with transcranial magnetic stimulation (TMS) and recording the later STC mismatch response with event-related optical signal (EROS), previous study demonstrated a causal IFC-to-STC functional connection in detecting a pitch or physical change. However, physical change detection can be achieved by memory comparison of the physical features and may not necessarily involve regularity/rule extraction and prediction.