[Rainwater harvesting effect of biocrusted soil-surfaces and the key influencing factors in the hilly region of Chinese Loess Plateau].

In the hilly region of Chinese Loess Plateau, rainwater harvesting is a common ecological engineering measure utilized to reduce soil erosion and amplify the efficiency of water resource utilization. However, the effects on rainwater harvesting and the chief influencing factors of biocrusts as a potential material are unclear. In this study, we conducted a field simulation experiment with intensities of 40, 60, 80, and 100 mm·h between bare soil and biocrusts developed in aeolian soils, with bare soil as a control to explore the differences of the initial abstraction time, cumulative rainfall amount, and rainfall harvesting efficiency.

A Recursive Non-Uniform Sampling Estimator for Asynchronous Nonlinear Systems.

In this paper, we consider the problem of asynchronous estimation in the presence of packet losses for the randomly sampling nonlinear system. Packet losses occur at the control input and at the measurement side. Firstly, the synchronization of the asynchronous sampling system is realized by weighting the state of the adjacent state update points.

Targeting epigenetic and post-translational modifications regulating pyroptosis for the treatment of inflammatory diseases.

Inflammatory diseases, including infectious diseases, diabetes-related diseases, arthritis-related diseases, neurological diseases, digestive diseases, and tumor, continue to threaten human health and impose a significant financial burden despite advancements in clinical treatment. Pyroptosis, a pro-inflammatory programmed cell death pathway, plays an important role in the regulation of inflammation. Moderate pyroptosis contributes to the activation of native immunity, whereas excessive pyroptosis is associated with the occurrence and progression of inflammation.

Integration of transcriptomic, proteomic, and metabolomic data to identify lncRNA rPvt1 associations in lipopolysaccharide-treated H9C2 cardiomyocytes.

Recent evidence has shown that the long non-coding RNA (lncRNA) rPvt1 is elevated in septic myocardial tissues and that its knockdown attenuates sepsis-induced myocardial injury. However, the mechanism underlying the role of rPvt1 in septic myocardial dysfunction has not been elucidated. In this study, we performed transcriptomic, proteomic, and metabolomic assays and conducted an integrated multi-omics analysis to explore the association between rPvt1 and lipopolysaccharide (Lipopolysaccharide)-induced H9C2 cardiomyocyte injury.

Fluoro-functionalized plant biomass adsorbent: Preparation and application in extraction of trace perfluorinated compounds from environmental water samples.

Perfluorinated compounds (PFCs) are toxic and widely present in the environment, and therefore effective adsorbents are required to remove PFCs from environmental water. In the present study, a new type of fluorinated biomass materials was synthesized via an ingenious fluorosilanization reaction. These adsorbents were applied for the adsorption of 13 typical PFCs, including perfluorocarboxylic acids (PFCAs) and perfluorosulfonic acids (PFSAs).

Roles of protein post-translational modifications in glucose and lipid metabolism: mechanisms and perspectives.

The metabolism of glucose and lipids is essential for energy production in the body, and dysregulation of the metabolic pathways of these molecules is implicated in various acute and chronic diseases, such as type 2 diabetes, Alzheimer's disease, atherosclerosis (AS), obesity, tumor, and sepsis. Post-translational modifications (PTMs) of proteins, which involve the addition or removal of covalent functional groups, play a crucial role in regulating protein structure, localization function, and activity. Common PTMs include phosphorylation, acetylation, ubiquitination, methylation, and glycosylation.

Transcriptome-wide identification of altered RNA mA profiles in cardiac tissue of rats with LPS-induced myocardial injury.

Purpose: Myocardial injury is a common complication in patients with endotoxaemia/sepsis, especially in children. Moreover, it develops through an unclear pathophysiological mechanism, and effective therapies are lacking. Recently, RNA modification, particularly -methyladenosine (mA) modification, has been found to be involved in various physiological processes and to play important roles in many diseases.

Functional status of pediatric patients with trauma and risk factors for mortality from a single center in China.

Introduction: The influence of reduced functional status has become increasingly relevant because of the gradual decline in mortality rate over the recent years. Nonetheless, only a few studies investigating the functional status of patients with trauma at hospital discharge have been conducted. This study aimed to identify the risk factors influencing the mortality rate in pediatric trauma survivors at a pediatric intensive care unit and analyze their functional status using the Functional Status Scale (FSS).

Kcnma1 is involved in mitochondrial homeostasis in diabetes-related skeletal muscle atrophy.

Uncontrolled diabetes causes a catabolic state with multi-organic complications, of which impairment on skeletal muscle contributes to the damaged mobility. Kcnma1 gene encodes the pore-forming α-subunit of Ca - and voltage-gated K channels of large conductance (BK channels), and loss-of-function mutations in Kcnma1 are in regards to impaired myogenesis. Herein, we observed a time-course reduction of Kcnma1 expression in the tibialis anterior muscles of leptin receptor-deficient (db/db) diabetic mice.

REGULATORY ROLE OF NONCODING RNA IN SEPSIS AND SEPSIS-ASSOCIATED ORGAN DYSFUNCTION: AN UPDATED SYSTEMATIC REVIEW.

Background: The exact molecular mechanisms underlying sepsis remain unclear. Accumulating evidence has shown that noncoding RNAs (ncRNAs) are involved in sepsis and sepsis-associated organ dysfunction (SAOD). Methods: We performed this updated systematic review focusing mainly on research conducted in the last 5 years regarding ncRNAs associated with sepsis and SAOD.

Non-Coding RNAs: Master Regulators of Inflammasomes in Inflammatory Diseases.

Emerging data indicates that non-coding RNAs (ncRNAs) represent more than just "junk sequences" of the genome and have been found to be involved in multiple diseases by regulating various biological process, including the activation of inflammasomes. As an important aspect of innate immunity, inflammasomes are large immune multiprotein complexes that tightly regulate the production of pro-inflammatory cytokines and mediate pyroptosis; the activation of the inflammasomes is a vital biological process in inflammatory diseases. Recent studies have emphasized the function of ncRNAs in the fine control of inflammasomes activation either by directly targeting components of the inflammasomes or by controlling the activity of various factors that control the activation of inflammasomes; consequently, ncRNAs may represent potential therapeutic targets for inflammatory diseases.

Design of a Single-Layer ±45° Dual-Polarized Directional Array Antenna for Millimeter Wave Applications.

A single-layer ±45° dual-polarized directional array antenna for millimeter wave (mm-wave) applications is designed in this communication. Based on the theory of orthogonal circularly polarized (CP) wave multiplexing, two ports of a series-fed dual CP array are fed with equal amplitudes, and the array can radiate a linearly polarized wave with ±45° polarization orientations through the adjustment of the feeding phase difference. As the two ports of the series-fed array are simultaneously excited, the antenna can achieve directional radiation.

Tension-Tension Fatigue Behavior of High-Toughness ZrTiCuAl Bulk Metallic Glass.

Bulk metallic glasses have application potential in engineering structures due to their exceptional strength and fracture toughness. Their fatigue resistance is very important for the application as well. We report the tension-tension fatigue damage behavior of a ZrTiCuAl bulk metallic glass, which has the highest fracture toughness among BMGs.

Risk factors for overt hepatic encephalopathy after transjugular intrahepatic portosystemic shunt creation in patients with liver cirrhosis.

Objective: This study aimed to determine the risk factors and establish a risk score for post-transjugular intrahepatic portosystemic shunt (TIPS) overt hepatic encephalopathy (OHE).

Methods: Altogether 299 and 62 cirrhotic patients receiving TIPS from January 2015 to March 2018 were divided into the derivation and validation cohorts, respectively. The data of the derivation cohort were analyzed for risk factors of post-TIPS OHE.

Temperature Effect on Fracture of a Zr-Based Bulk Metallic Glass.

Bulk metallic glass (BMGs) is highly expected for applications in engineering structures due to their superior mechanical properties. The fracture toughness of some BMGs was investigated at cryogenic and at elevated temperatures. However, the mechanism of the temperature-dependence of BMG toughness still remains elusive.

[Features of new-onset organ dysfunction in children with sepsis].

Objective: To study the features of new-onset organ dysfunction in children with sepsis in the pediatric intensive care unit (PICU).

Methods: A retrospective analysis was performed for the clinical data of children with sepsis who were admitted to the PICU from 2015 to 2016. There were 34 children with severe sepsis and 69 with non-severe sepsis, and the two groups were compared in terms of the incidence rate of new-onset organ dysfunction and the functional status on admission and at discharge.

[Variation of STAT3 Gene in Myleproliferative Neoplasms and Its Significance].

Objective: To detect the mutation and single nucleotide polymorphisms of STAT3 gene in the patients with myeloproliferative neoplasms (MPN), and to analyze the correlation between STAT3 gene and the subtypes of MPN.

Methods: A total of 147 patients with MPN were selected, including 28 patients with polycythaemia vera (PV), 46 patients with essential thrombocythemia (ET), 10 patients with primary myelofibrosis (PMF), and 63 patients with chronic myeloid leukemia (CML); and 88 healthy persons were used as normal control. DNA of all cases was extracted from bone marrow or peripheral blood, and JAK2V617F gene mutation was detected by allele-specific PCR, then 23 exons of STAT3 gene were amplified by PCR.

[Artesunate Suppresses Cell Proliferation of THP-1 Cells by Inducing Apoptosis].

Objective: To investigate whether Artesunate(ART) can inhibit the proliferation of THP-1 cells and to explore the potential mechanism of its anti-leukemia effect.

Methods: THP-1 cells were treated with 5 concentrations of Artesunate for 24 h, 48 h or 72 h. The viability of cells was detected with CCK-8 assay, apoptosis was assessed by using flow cytometry, and the STAT3, Caspase3 and Caspase8 protein levels were measured with Western blot .

KI-catalyzed C-S bond formation via an oxidation relay strategy: efficient access to various α-thio-β-dicarbonyl compounds.

An efficient and practical methodology to obtain α-thio-β-dicarbonyl compounds was presented under alkaline conditions via potassium iodide (KI) catalysis; various symmetrical/unsymmetrical 1,3-dicarbonyl compounds were obtained under an aerobic atmosphere in moderate to excellent yields, with good functional group tolerance. Notably, a widely used anti-inflammatory drug butazodine could be modified with our protocol, even on a gram scale.

[Clinical features and prognostic factors in children with fulminant myocarditis].

Objective: To investigate the clinical features and prognostic factors in children with fulminant myocarditis.

Methods: The clinical data of 24 children with fulminant myocarditis were retrospectively analyzed. According to the prognosis, these children were classified into two groups: survival (n=12) and death (n=12).

Inducing transparency with large magnetic response and group indices by hybrid dielectric metamaterials.

We present metamaterial-induced transparency (MIT) phenomena with enhanced magnetic fields in hybrid dielectric metamaterials. Using two hybrid structures of identical-dielectric-constant resonators (IDRs) and distinct-dielectric-constant resonators (DDRs), we demonstrate a larger group index (ng~354), better bandwidth-delay product (BDP~0.9) than metallic-type metamaterials.

An anisotropic negative refractive index medium operated at multiple-angle incidences.

Recently metamaterials have been demonstrating new physics to enable various unprecedented electromagnetic properties, but pratically they are so sensitive to incident angles of the external excitation that their applications are restricted. Therefore, we present an anisotropic negative refractive index medium operated at multiple-angle incidences (NRIM for MAI) to ease such a burden. Both the simulated and measured transmittance, reflectance and the corresponding material parameters indicate that our structure does possess the anisotropic negative refractive index with respect to different incident angles.

A scalable admission control scheme based on time label.

Resource reservation protocols allow communicating hosts to reserve resources such as bandwidth to offer guaranteed service. However, current resource reservation architectures do not scale well for a large number of flows. In this paper, we present a simple reservation protocol and a scalable admission control algorithm, which can provide QoS guarantees to individual flows without per-flow management in the network core.

A modified multitarget adaptive array algorithm for wireless CDMA system.

The paper presents a modified least squares despread respread multitarget constant modulus algorithm (LS-DRMTCMA). The cost function of the original algorithm was modified by the minimum bit error rate (MBER) criterion. The novel algorithm tries to optimize weight vectors by directly minimizing bit error rate (BER) of code division multiple access (CDMA) mobile communication system.