Barrier Polarity Reversal Based on Interfacial Modification of Au Nanoparticles for Nonvolatile Multilevel Memory and Optoelectronic Synapses.

Optoelectronic synaptic devices, integrating light sensing and information processing capabilities, have emerged as advantageous tools for the implementation of visual neuromorphic computing. However, the transient light-triggered response characteristic typically results in unstable memory retention times and restricted current response ranges, posing significant challenges to the development and practical application of neural network systems. In response to these limitations, this study developed a nonvolatile optoelectronic memory based on the indium tin oxide (ITO)/Au nanoparticles (NPs)/amorphous GaO (a-GaO)/Pt structure.

 sp. nov. (Bacillariophyta), a new marine monoraphid diatom species from the coast of Guangxi, China.

A new marine monoraphid diatom species, , is described from the coast of Guangxi, China. The detailed morphology of this epipsammic diatom is studied by using both light and scanning electron microscopy. differs from congeners by a combination of morphological features including capitate apices, multiseriate striae, a small central area on the raphe valve and an oblong sinus on the rapheless valve.

Anti-PD-1 combined with hypomethylating agent and CAG regimen bridging to allogeneic hematopoietic stem cell transplantation: a novel strategy for relapsed/refractory acute myeloid leukemia.

Introduction: The prognosis of relapsed/refractory acute myeloid leukemia (r/rAML) is dismal, and allogeneic hematopoietic stem cell transplant (allo-HSCT) is a potential cure. Combining anti-PD-1, hypomethylating agent (HMA), and CAG (cytarabine, aclarubicin/idarubicin, granulocyte colony-stimulating factor) regimen has showed primary efficacy in r/rAML. However, pre-transplant exposure to anti-PD-1 may lead to severe graft-versus-host disease (GVHD).

Multi-channel electron transfer induced by polyvanadate in metal-organic framework for boosted peroxymonosulfate activation.

Catalytic peroxymonosulfate (PMS) activation processes don't solely rely on electron transfer from dominant metal centers due to the complicated composition and interface environment of catalysts. Herein the synthesis of a cobalt based metal-organic framework containing polyvanadate [VO] cluster, Co(VO)(bpy) (bpy = 4,4'-bipyridine), is presented. The catalyst demonstrates superior degradation activity toward various micropollutants, with higher highest occupied molecular orbital (HOMO), via nonradical attack.

Strategy to Efficient Photodynamic Therapy for Antibacterium: Donor-Acceptor Structure in Hydrogen-Bonded Organic Framework.

While the construction of a donor-acceptor (D-A) structure has gained great attention across various scientific disciplines, such structures are seldomly reported within the field of hydrogen-bonded organic frameworks (HOFs). Herein, a D-A based HOF is synthesized, where the adjacent D-A pairs are connected by hydrogen bonds instead of the conventionally employed covalent bonds. This structural feature imparts material with a reduced energy gap between excited state and triplet state, thereby facilitating the intersystem crossing (ISC) and boosting the generation rate of single oxygen (quantum yield = 0.

High spin axion insulator.

Axion insulators possess a quantized axion field θ = π protected by combined lattice and time-reversal symmetry, holding great potential for device applications in layertronics and quantum computing. Here, we propose a high-spin axion insulator (HSAI) defined in large spin-s representation, which maintains the same inherent symmetry but possesses a notable axion field θ = (s + 1/2)π. Such distinct axion field is confirmed independently by the direct calculation of the axion term using hybrid Wannier functions, layer-resolved Chern numbers, as well as the topological magneto-electric effect.

Two new diatom species of the genus (Bacillariophyceae) from the coast of China and two new combinations for the genus.

Two new diatom species belonging to the genus are described, and These two species were compared in detail with congeners. is distinguished by its high stria density and small size. This species was found so far to be epiphytic only on the eelgrass collected from Qingdao Bay (Yellow Sea).

Inhibition of calcium-sensing receptor by its antagonist promotes gastrointestinal motility in a Parkinson's disease mouse model.

Background: The Calcium-sensing receptor (CaSR) participates in the regulation of gastrointestinal (GI) motility under normal conditions and might be involved in the regulation of GI dysmotility in patients with Parkinson's disease (PD).

Methods: CaSR antagonist-NPS-2143 was applied in in vivo and ex vivo experiments to study the effect and underlying mechanisms of CaSR inhibition on GI dysmotility in the MPTP-induced PD mouse model.

Findings: Oral intake of NPS-2143 promoted GI motility in PD mice as shown by the increased gastric emptying rate and shortened whole gut transit time together with improved weight and water content in the feces of PD mice, and the lack of influence on normal mice.

Ultrafast removal of organics peroxymonosulfate activation over CoP/TD hollow spheres derived from ZIF-67.

CoP/tetrasodium diphosphate (TD) derived from ZIF-67/sodium phytate was newly developed and synthesized, and exhibited excellent degradation ability toward various refractory organics peroxymonosulfate activation. A corresponding reaction mechanism was proposed. In addition, a continuous-flow operation of phenol degradation was realized.

Effect of Guanxin Danshen Dripping Pills on Coronary Heart Disease Comorbid with Depression or Anxiety: The ADECODE-Real World Study.

Objective: To evaluate the efficacy of Guanxin Danshen Dripping Pill (GXDSDP) in treating anxiety and depression in patients with coronary heart disease (CHD).

Methods: A total of 1,428 patients diagnosed with CHD screened for anxiety, depression, and quality of life (QOL) at baseline received 0.4 g of GXDSDP treatment 3 times per day and returned for monthly reassessment.

Morphology and molecular phylogeny of sp. nov. (Pleurosigmataceae), a new tropical pelagic species from the Western Pacific Ocean.

A new species of pelagic diatom, , is described from the tropical Western Pacific Ocean. It has the typical features of , including a slightly sigmoid raphe, intersected transverse and oblique striae, and loculate areolae with external opening slits and internal poroids. Morphologically, belongs to a species group of with lanceolate valves, including Heiden & Kolbe, W.

The Classification, Molecular Structure and Biological Biosynthesis of Flavonoids, and Their Roles in Biotic and Abiotic Stresses.

With the climate constantly changing, plants suffer more frequently from various abiotic and biotic stresses. However, they have evolved biosynthetic machinery to survive in stressful environmental conditions. Flavonoids are involved in a variety of biological activities in plants, which can protect plants from different biotic (plant-parasitic nematodes, fungi and bacteria) and abiotic stresses (salt stress, drought stress, UV, higher and lower temperatures).

[Efficacy and Safety of Allogeneic Hematopoietic Stem Cell Transplantation with Decitabine-containing Regimen in Myelodysplastic Syndromes and Myelodysplastic Syndromes Transformed Acute Myeloid Leukemia].

Objective: To evaluate the efficacy and safety of allogeneic hematopoietic stem cell transplantation (allo-HSCT) with decitabine (Dec)-conditioning regimen in the treatment of myelodysplastic syndrome (MDS) and MDS transformed acute myeloid leukemia (MDS-AML).

Methods: The characteristics and efficacy data of 93 patients with MDS and MDS-AML who received allo-HSCT in our center from April 2013 to November 2021 were retrospectively analyzed. All patients were administered by myeloablative conditioning regimen containing Dec (25 mg/m /d×3 d).

Transcriptome and metabolome analyses reveal molecular mechanisms of anthocyanin-related leaf color variation in poplar () cultivars.

Introduction: Colored-leaf plants are increasingly popular for their aesthetic, ecological, and social value, which are important materials for research on the regulation of plant pigments. However, anthocyanin components and the molecular mechanisms of anthocyanin biosynthesis in colored-leaf poplar remain unclear. Consequently, an integrative analysis of transcriptome and metabolome is performed to identify the key metabolic pathways and key genes, which could contribute to the molecular mechanism of anthocyanin biosynthesis in the colored-leaf cultivars poplar.

Exploration of Ligand-Centered Hydride Transfer in La/Y-Catalyzed Deoxygenative Reduction of Tertiary Amides with Pinacolborane.

A number of rare-earth metals and actinides have proven to be active in a wide variety of atom-efficient transformations. As compared to the related organometallic catalysts, the detailed mechanisms for the rare-earth metal-catalyzed reactions remain largely unexplored. Herein, the detailed catalyst activation process and reaction mechanisms of deoxygenative reduction of amides with pinacolborane (HBpin) catalyzed by Y[N(TMS)] and La[N(TMS)] complexes as well as a La(O)acac cluster are investigated by density functional theory calculations.

Protective effects and mechanism of puerarin targeting PI3K/Akt signal pathway on neurological diseases.

Neurological diseases impose a tremendous and increasing burden on global health, and there is currently no curative agent. Puerarin, a natural isoflavone extracted from the dried root of Pueraria montana var. Lobata (Willd.

RNA-seq reveals the role of miR-199a-3p in regulating inflammation of bovine mammary epithelial cells.

MicroRNAs (miRNAs) are involved in the regulation of a variety of biological processes. However, the research on the regulatory role of bovine mammary epithelial cells (bMECs) is scarce. To date, there are no reports about the role of miR-199a-3p in bMECs.

Circulating mitochondrial DNA is associated with anemia in newly diagnosed hematologic malignancies.

Recent reports discovered that red blood cells (RBCs) could scavenge cell-free mitochondrial DNA (mtDNA), which drives the accelerated erythrophagocytosis and innate immune activation characterized by anemia and inflammatory cytokine production. However, the clinical value of the circulating mtDNA copy number alterations in hematologic malignancies is poorly understood. Our data showed that in comparison to healthy group, the patients group had significantly higher mtDNA and histone H4 levels.

[Relationship between epiphyllous bud of tropical waterlily ()umbilics and carbohydrate meta-bolism in different parts of leaves].

To understand the development mechanism of the epiphyllous bud of waterlily, we examined the morphological anatomy of the leaf-navel epiphyllous bud by paraffin section technique at four stages, and compared the differences of carbohydrate metabolism between viviparous and non-viviparous waterlily leaves. Three tropical waterlily cultivars of were used, including two viviparous cultivars 'Margaret Mary', 'Ruby', and a non-viviparous cultivar 'Pink Star'. The results showed that parenchyma cells below the epidermis of leaf-navel divided and grew continuously after the leaf unfolded, forming a closely arranged cell cluster in viviparous waterlily and raised upward to a spherical shape.

Recent research on immunotherapy for anti-N-methyl-D-aspartate receptor encephalitis.

Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a central nervous system disease characterized by neurological and psychiatric symptoms. Immunotherapy is the basic treatment for this disease, including first- and second-line therapies for the acute stage and the long-course therapy for the chronic stage. Anti-NMDAR encephalitis often has a good prognosis, but some patients may still have neurological dysfunction due to poor response to current immunotherapy.

Genome-wide identification and characterization of PdbHLH transcription factors related to anthocyanin biosynthesis in colored-leaf poplar (Populus deltoids).

Basic helix-loop-helix (bHLH) proteins are transcription factors (TFs) that have been shown to regulate anthocyanin biosynthesis in many plant species. However, the bHLH gene family in Populus deltoids has not yet been reported. In this study, 185 PdbHLH genes were identified in the Populus deltoids genome and were classified into 15 groups based on their sequence similarity and phylogenetic relationships.

Mechanistic Insights into the Electrochemical Reduction of CO and N on the Regulation of a Boron Nitride Defect-Derived Two-Dimensional Catalyst using Density Functional Theory Calculations.

Electrochemical reductions of CO (ECRR) and N (ENRR) can not only reduce CO emissions in the air but also make use of N and HO, the most extensive resources on earth, to produce high value-added chemicals, which has become one of the hot research directions. In this study, the formation energy () and dissolution potential () of 96 two-dimensional catalysts derived from different defect sites of monoclinic crystal boron nitride (BN) were calculated, and the catalysts with thermodynamic and electrochemical stability were selected. The suitable catalysts for producing HCOOH (Ga/In@N-BN), CO (Sn@BN), and CHOH (Co@N-BN) by ECRR and NH (Fe@BN) by ENRR were predicated based on a selective calculation method.

Robust Cr(VI) reduction over hydroxyl modified UiO-66 photocatalyst constructed from mixed ligands: Performances and mechanism insight with or without tartaric acid.

Hydroxyl modified UiO-66 ((OH)-UiO-66-X%, X represents the mass content ratio of introduced 2,5-dihydroxyterephthalic acid) was prepared via a solvothermal reaction between zirconium tetrachloride, benzene-1,4-dicarboxylic acid (HBDC), as well as 2,5-dihydroxyterephthalic acid (HBDC-(OH)). It was found that hydroxyl groups can act as the intramolecular hole scavenger to boost the photo-induced charge carrier separation to enhance Cr(VI) reduction. The photocatalytic Cr(VI) reduction activities of (OH)-UiO-66-X% were investigated upon the irradiation of low-power ultraviolet LED light.