Publications by authors named "Yu-Han Yan"

Geographic entity matching is an important means for multi-source spatial data fusion and information association and sharing. Corresponding matching methods have been designed by existing studies for different types of entity data characteristics, such as line and area. However, these approaches are often limited in the generalization ability for matching heterogeneous data from multiple sources and the accuracy for complex pattern matching.

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Article Synopsis
  • This study investigated the potential of a new Mycobacterium tuberculosis antigen called Rv0674 for diagnosing and vaccinating against tuberculosis (TB).* -
  • Results showed that TB patients had a stronger immune response (higher IgG levels) to Rv0674 compared to healthy controls, with decent sensitivity (77.1%) and specificity (81.1%) in serological tests.* -
  • The research suggests Rv0674 could be a promising candidate for a TB diagnosis tool and vaccine, as it activates important immune responses in test subjects.*
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The accumulation of aggregated amyloid-β (Aβ) in the brain is the first critical step in the pathogenesis of Alzheimer's disease (AD), which also includes synaptic impairment, neuroinflammation, neuronal loss, and eventual cognitive defects. Emerging evidence suggests that impairment of Aβ phagocytosis and clearance is a common phenotype in late-onset AD. Rutin (quercetin-3-rutinoside) has long been investigated as a natural flavonoid with different biological functions in some pathological circumstances.

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