Revisiting Endoreversible Carnot Engine: Extending the Yvon Engine.

Curzon and Ahlborn's 1975 paper, a pioneering work that inspired the birth of the field of finite-time thermodynamics, unveiled the efficiency at maximum power (EMP) of the endoreversible Carnot heat engine, now commonly referred to as the Curzon-Ahlborn (CA) engine. Historically, despite the significance of the CA engine, similar findings had emerged at an earlier time, such as the Yvon engine proposed by J. Yvon in 1955 that shares the exact same EMP, that is, the CA efficiency ηCA.

Minimal Model for Carnot Efficiency at Maximum Power.

Carnot efficiency sets a fundamental upper bound on the heat engine efficiency, attainable in the quasistatic limit, albeit at the cost of completely sacrificing power output. Here, we present a minimal heat engine model that can attain Carnot efficiency while achieving maximum power output. We unveil the potential of intrinsic divergent physical quantities within the working substance, such as degeneracy, as promising thermodynamic resources to break through the universal power-efficiency trade-off imposed by nonequilibrium thermodynamics for conventional heat engines.

Engineering ratchet-based particle separation via extended shortcuts to isothermality.

Microscopic particle separation plays a vital role in various scientific and industrial domains. Conventional separation methods relying on external forces or physical barriers inherently exhibit limitations in terms of efficiency, selectivity, and adaptability across diverse particle types. To overcome these limitations, researchers are constantly exploring new separation approaches, among which ratchet-based separation is a noteworthy method.

Activation of non-classical Wnt signaling pathway effectively enhances HLA-A presentation in acute myeloid leukemia.

Objective: The escape from T cell-mediated immune surveillance is an important cause of death for patients with acute myeloid leukemia (AML). This study aims to identify clonal heterogeneity in leukemia progenitor cells and explore molecular or signaling pathways associated with AML immune escape.

Methods: Single-cell RNA sequencing (scRNA-seq) was performed to identified AML-related cellular subsets, and intercellular communication was analyzed to investigate molecular mechanisms associated with AML immune escape.

Temperature fluctuations in mesoscopic systems.

Temperature is a fundamental concept in thermodynamics. In macroscopic thermodynamics, systems possess their own intrinsic temperature which equals the reservoir temperature when they equilibrate. In stochastic thermodynamics for simple systems at the microscopic level, thermodynamic quantities other than temperature (a deterministic parameter of the reservoir) are stochastic.

Predictive validation of existing bleeding and thromboembolic scores in elderly patients with comorbid atrial fibrillation and acute coronary syndrome.

Background: The validation of various risk scores in elderly patients with comorbid atrial fibrillation (AF) and acute coronary syndrome (ACS) has not been reported. The present study compared the predictive performance of existing risk scores in these patients.

Methods: A total of 1252 elderly patients with AF and ACS comorbidities (≥ 65 years old) were consecutively enrolled from January 2015 to December 2019.

Experimental test of power-efficiency trade-off in a finite-time Carnot cycle.

The Carnot cycle is a prototype of an ideal heat engine cycle to draw mechanical energy from the heat flux between two thermal baths with the maximum efficiency, dubbed as the Carnot efficiency η_{C}. Such efficiency is reached by thermodynamical equilibrium processes with infinite time, accompanied unavoidably with vanishing power-energy output per unit time. The quest to acquire high power leads to an open question of whether a fundamental maximum efficiency exists for finite-time heat engines with given power.

Applying OHSA to Detect Road Accident Blackspots.

With increasing numbers of crashes and injuries, understanding traffic accident spatial patterns and identifying blackspots is critical to improve overall road safety. This study aims at detecting blackspots using optimized hot spot analysis (OHSA). Traffic accidents were classified by their participants and severity to explore the relationship between blackspots and different types of accidents.

Minimal energy cost to initialize a bit with tolerable error.

Landauer's principle imposes a fundamental limit on the energy cost to perfectly initialize a classical bit, which is only reached under the ideal operation with infinitely long time. The question on the cost in the practical operation for a bit has been raised under the constraint by the finiteness of operation time. We discover a raise-up of energy cost by L^{2}(ε)/τ from the Landaeur's limit (k_{B}Tln2) for a finite-time τ initialization of a bit with an error probability ε.

Optimizing thermodynamic cycles with two finite-sized reservoirs.

We study the nonequilibrium thermodynamics of a heat engine operating between two finite-sized reservoirs with well-defined temperatures. Within the linear response regime, it is found that the uniform temperature of the two reservoirs at final time τ is bounded from below by the entropy production σ_{min}∝1/τ. We discover a general power-efficiency tradeoff depending on the ratio of heat capacities (γ) of the reservoirs for the engine, and a universal efficiency at maximum average power of the engine for arbitrary γ is obtained.

Effect of Finite-Size Heat Source's Heat Capacity on the Efficiency of Heat Engine.

Heat engines used to output useful work have important practical significance, which, in general, operate between heat baths of infinite size and constant temperature. In this paper, we study the efficiency of a heat engine operating between two finite-size heat sources with initial temperature difference. The total output work of such heat engine is limited due to the finite heat capacity of the sources.

Experimental Test of the 1/τ-Scaling Entropy Generation in Finite-Time Thermodynamics.

The finite-time dynamics, apart from its fundamental importance in nonequilibrium thermodynamics, is of great significance in designing heat engine cycles. We build an experimental apparatus to test the predicted long-time 1/τ scaling of the irreversible entropy generation in the finite-time (τ) thermodynamic process by compressing dry air in a temperature-controlled water bath. We present the first direct experimental validation of the scaling, utilized in many finite-time thermodynamic models at the long-time regime.

Maximum entropy approach to reliability.

The aging process is a common phenomenon in engineering, biological, and physical systems. The hazard rate function, which characterizes the aging process, is a fundamental quantity in the disciplines of reliability, failure, and risk analysis. However, it is difficult to determine the entire hazard function accurately with limited observation data when the degradation mechanism is not fully understood.

Optimal operating protocol to achieve efficiency at maximum power of heat engines.

Efficiency at maximum power has been investigated extensively, yet the practical control scheme to achieve it remains elusive. We fill this gap with a stepwise Carnot-like cycle, which consists of the discrete isothermal process (DIP) and adiabatic process. With DIP, we validate the widely adopted assumption of the C/t relation of the irreversible entropy generation S^{(ir)} and show the explicit dependence of the coefficient C on the fluctuation of the speed of tuning energy levels as well as the microscopic coupling constants to the heat baths.

Quantum thermodynamic cycle with quantum phase transition.

With the Lipkin-Meshkov-Glick (LMG) model as an illustration, we construct a thermodynamic cycle composed of two isothermal processes and two isomagnetic field processes, and we study the thermodynamic performance of this cycle accompanied by the quantum phase transition (QPT). We find that for a finite particle system working below the critical temperature, the efficiency of the cycle is capable of approaching the Carnot limit when the external magnetic field λ_{1} corresponding to one of the isomagnetic processes reaches the cross point of the ground states' energy level, which can become the critical point of the QPT in the large-N limit. Our analysis proves that the system's energy level crossings at low-temperature limits can lead to a significant improvement in the efficiency of the quantum heat engine.

Antisense knockdown of pyruvate dehydrogenase kinase promotes the neutral lipid accumulation in the diatom Phaeodactylum tricornutum.

Background: Microalgae have been an emerging biofuel resource; however, the germplasm improvement has been slow due to the lack of molecular tools. Pyruvate dehydrogenase kinase (PDK) deactivates the pyruvate dehydrogenase complex (PDC) which catalyzes the oxidative decarboxylation of pyruvate. Acetyl-CoA production via PDC is important in plant tissues that are active in fatty acid synthesis.

Proteomics to reveal metabolic network shifts towards lipid accumulation following nitrogen deprivation in the diatom .

The marine diatom is attracting considerable interest as a candidate for biofuel production due to its fast growth and high lipid content. Nitrogen deficiency can increase the lipid content in certain microalgae species, including . .

Molecular and cellular mechanisms of neutral lipid accumulation in diatom following nitrogen deprivation.

Background: Nitrogen limitation can induce neutral lipid accumulation in microalgae, as well as inhibiting their growth. Therefore, to obtain cultures with both high biomass and high lipid contents, and explore the lipid accumulation mechanisms, we implemented nitrogen deprivation in a model diatom Phaeodactylum tricornutum at late exponential phase.

Results: Neutral lipid contents per cell subsequently increased 2.

[Relationship between sperm motility parameters and sperm morphology].

Objective: To evaluate the relationship between sperm motility parameters and sperm morphology.

Methods: Seven hundred and eighty-three semen samples were tested. Sperm motility parameters were analyzed by computer-aided sperm analysis (CASA) , and sperm morphology assessed by automated sperm morphology analyzer (ASMA).