[A Method for Fine Mapping of Carbon Emissions from Regional Land Use Change and Its Application].

Land use changes are always patchy and widespread within a region, making it a challenge to identify the point-scale pressure of reducing carbon emissions from land use/cover change （LUCC）. The carbon emission observation index （CEOI） was thus proposed to conduct the point-scale comparability analysis, which was based on the unique net C flux effects of conversions between two different land use types. Then, the spatial-temporal characteristics of land use changes and the resulting pressure of reducing carbon emissions were studied in the Weihe River Basin of China, which adopted the LUCC data from 2000 to 2020 and models of the Markov transition matrix （MTM）, compound carbon emission coefficients （CEC） of various types of land use changes, and the CEOI-based classification method on point-scale pressure of reducing carbon emissions.

A novel variant (p.A524P) in Spastin is responsible for a Chinese family with hereditary spastic paraplegia.

Background: Hereditary spastic paraplegia (HSP) represents a group of monogenic neurodegenerative disorders characterized by high clinical and genetic heterogeneity. HSP is characterized by slowly progressing hypertonia of both lower extremities, spastic gait, and myasthenia. The most prevalent autosomal dominant form of HSP, known as spastic paraplegia 4 (SPG4), is attributed to variants in the spastin (SPAST) gene.

Development and evaluation of a bivalent vaccine based on recombinant newcastle disease virus expressing infectious bursal disease virus VP2L-CH3-CH4 in SPF chickens.

Newcastle disease (ND) and infectious bursal disease (IBD) are two viral infectious diseases that are extremely damaging to the poultry industry and are widespread throughout the world. It is necessary to develop a safe and effective vaccine against IBD and ND because vaccination is an effective preventive measure. It has been discovered that recombinant proteins expressed by an expression system in which a fragment of mammalian Immunoglobulin G (IgG) Fragment crystallizable (Fc) is linked to a segment of a gene have antibody-like properties that increase the exogenous protein's serum half-life.

Korean version of the caregiver quality of life index-cancer (CQOLC-K).

Objective: The aim of this study was to develop and evaluate the internal consistency and construct validity of a Korean version of the Caregiver Quality of Life Index-Cancer (CQOLC-K).

Methods: The CQOLC-K was administered to 270 caregivers, along with the Medical Outcomes Study Short Form-36 (SF-36) and the Beck Depression Inventory (BDI).

Results: Internal consistency of the CQOLC-K (0.