Publications by authors named "Yu-Han Dong"

Chronic inflammation is a common factor in the pathological processes of multiple human diseases. EPS-LM, an exopolysaccharide (EPS) from the Cordyceps sinensis fungus Cs-HK1, has shown notable anti-inflammatory activities in previous studies. This study aimed to investigate the major signaling events mediating the anti-inflammatory effects of EPS-LM in lipopolysaccharide (LPS)-stimulated RAW 264.

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  • * This scaffold consists of three components: a porous structure for bone, a hydrogel for cartilage, and oriented fibers for tendon, all engineered to promote cell differentiation and healing.
  • * Results show that the scaffold not only matches the mechanical properties of TBI but also enhances the healing process in a rat model, indicating its potential for effective TBI regeneration.
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Objective: To investigate the expression of SCD1 in TFE3-rRCC and its effect on the proliferation and migration of TFE3-rRCC cells.

Methods: GEPIA database was used to analyze the expression level of SCD1 in different tumors and its effect on the prognosis of patients. The expression levels of SCD1 in TFE3-rRCC patients and cell lines UOK109 and UOK120 were detected by QPCR and Western blot.

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  • New antibiotics are needed because some bacteria are becoming resistant to current ones, making them less effective.
  • Famotidine, a drug that helps reduce stomach acid, can boost the power of a specific antibiotic called rifampicin against a tough bacteria called A. baumannii.
  • In tests with insects and mice, famotidine helped more animals survive infections, suggesting it could be a promising new way to fight these hard-to-treat bacterial infections.
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  • - The study focuses on the need for new strategies to combat multidrug-resistant bacterial pathogens, highlighting the potential of proline-rich antimicrobial peptides (PrAMPs) like OM19r to enhance existing antibiotics’ effectiveness.
  • - Through various experiments, OM19r was shown to significantly increase the antibacterial activity of gentamicin against resistant bacteria by altering membrane permeability and disrupting protein synthesis.
  • - The research concludes that combining OM19r with gentamicin provides a promising therapeutic approach against multidrug-resistant bacteria, effectively blocking protein synthesis and improving treatment outcomes in animal models.
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In recent years, although low-dimensional hybrid lead halides have received great attention due to the fascinating photoluminescent (PL) properties, the research is still on the early stage and only limited phases have been explored and characterized. Here, by introducing heterometals as mixed structural compositions and optical activity centers, we prepared a series of low-dimensional hybrid heterometallic halides, namely as, [(Me)-DABCO]CuPbI, [(Me)-DABCO]MPbI (M = Cu and Ag) and [(Me)-DABCO]AgPbBr (Me = methyl group, DABCO = 1,4-diazabicyclo[2.2.

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Here, we prepared the first series of 3D hybrid iodoplumbates with novel porous frameworks of [Pb8I21]5- directed by transition metal complex (TMC) cationic dyes of [TM(2.2-bipy)3]2+. The microporous materials exhibit outstanding visible light-driven photoelectric properties due to the effective photosensitization of the TMC dyes.

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