Publications by authors named "Yu-Gui Lian"
Article Synopsis
- Regorafenib (R) and fruquintinib (F) are current third-line treatments for colorectal cancer, but their effectiveness is limited, leading to interest in combining them with immune checkpoint inhibitors.
- A study involving 313 metastatic colorectal cancer patients compared the efficacy of F, R, F plus a PD-1 inhibitor, and R plus PD-1 inhibitors, highlighting that the combination therapy showed improved outcomes, particularly with the F plus PD-1 inhibitor (FP) group.
- The results indicated that FP had better disease control rates and longer progression-free survival compared to F and RP, while RP did not demonstrate significant survival benefits compared to R.
Reactive Astrocytes in Central Nervous System Injury: Subgroup and Potential Therapy.
Front Cell Neurosci
December 2021
Traumatic central nervous system (CNS) injury, which includes both traumatic brain injury (TBI) and spinal cord injury (SCI), is associated with irreversible loss of neurological function and high medical care costs. Currently, no effective treatment exists to improve the prognosis of patients. Astrocytes comprise the largest population of glial cells in the CNS and, with the advancements in the field of neurology, are increasingly recognized as having key functions in both the brain and the spinal cord.
View Article and Find Full Text PDFOddi sphincter preserved cholangioplasty with hepatico-subcutaneous stoma for hepatolithiasis.
World J Gastroenterol
December 2015
Aim: To evaluate the long-term outcomes of Oddi sphincter preserved cholangioplasty with hepatico-subcutaneous stoma (OSPCHS) and risk factors for recurrence in hepatolithiasis.
Methods: From March 1993 to December 2012, 202 consecutive patients with hepatolithiasis underwent OSPCHS at our department. The Oddi sphincter preserved procedure consisted of common hepatic duct exploration, stone extraction, hilar bile duct plasty, establishment of subcutaneous stoma to the bile duct.