Publications by authors named "Yu-Fang Hsiao"
Oral submucous fibrosis (OSMF) is a chronic inflammatory disease and a potentially malignant oral disorder, characterized by fibrosis of the oral mucosa. TGF-β signaling pathways have been implicated in the development of OSMF, with areca nut extract (ANE) contributing to the disease progression. Simvastatin, a statin drug, has demonstrated anti-fibrotic properties in various fibrotic conditions.
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- The study used a microfluidic device to investigate how hydraulic pressure affects H9c2 cardiomyoblast cells.
- A pressure of 170 mm Hg resulted in increased cell size and higher levels of atrial natriuretic peptide expression.
- The presence of a focal adhesion kinase inhibitor diminished the impact of hydraulic pressure, suggesting a new potential therapeutic approach for treating heart issues related to high blood pressure.