PPy@MIL-100 Nanoparticles as a pH- and Near-IR-Irradiation-Responsive Drug Carrier for Simultaneous Photothermal Therapy and Chemotherapy of Cancer Cells.

A medical nanoplatform with small size, low cost, biocompatibility, good biodegradability, and, in particular, multifunctionality has attracted much attention in the exploration of novel therapeutic methodologies. As an emerging material of self-assembled porous structure, metal-organic frameworks (MOFs) have high expectations because of their special properties compared to traditional porous materials. Therefore, integration of MOFs and functional materials is leading to the creation of new multifunctional composites/hybrids.

Synthesis of hollow hydroxyapatite nanospheres by the control of nucleation and growth in a two phase system.

Hollow hydroxyapatite nanospheres were prepared by a two-phase approach by controlling nucleation and crystal growth processes. The cavities of hollow HA provide potential applications as new kinds of containers for carrying, filling in, or encapsulating other materials, thus constructing a multifunctional system with good biocompatibility.