Whole mitochondrial genome sequence of a rat pancreatic adenocarcinoma CRL-2389 LTPA cell line.

Pancreatic adenocarcinoma is the fifth leading cause of cancer death in the world. We sequenced a complete mitochondrial genome sequence of a rat pancreatic tumor CRL-2389 LTPA cell line for the first time. The total length of the mitogenome was 16,314 bp and coding 13 protein-coding genes, two ribosomal RNA genes, 22 transfer RNA genes.

In vitro evidence of baicalein's inhibition of the metabolism of zidovudine (AZT).

Background: Herb-drug interaction (HDI) has been regarded as a key factor limiting the clinical application of herbs and drugs.

Aims: Potential baicalein-zidovudine (AZT) interaction was predicted in the present study.

Methods: In vitro evaluation of baicalein's inhibition towards human liver microsomes (HLMs)-catalyzed metabolism of zidovudine (AZT) was performed.

[Observation on the efficacy of acupuncture and fire needle therapy for hand osteoarthritis].

Objective: To verify the clinical efficacy of shu-stream point acupuncture combined with fire needle therapy in the treatment of hand osteoarthritis.

Methods: Eighty cases were randomized into an acupuncture group (shu-stream point acupuncture combined with fire needle therapy) and a medication group(votalin emulgel). For the 42 cases in the acupuncture group, acupuncture at shu-stream points on the three yang meridians of the hand including Sanjian (LI 3), Zhongzhu (TE 3), Houxi (SI 3) and fire needle at Ashi points were applied, the treatments were given once every other day, 15 times as a treatment course.