Publications by authors named "Yu-Chi Hsiao"
Article Synopsis
- Pseudohyperkalemia, a condition characterized by falsely high potassium levels, can be confused with true hyperkalemia, leading to unnecessary treatments; it is important to differentiate between the two.
- A study analyzed 1188 blood samples and found that pneumatic tube transportation was associated with a higher occurrence of pseudohyperkalemia, particularly when white blood cell (WBC) counts were elevated (≥ 100 × 10/μL).
- The results indicate that for every increase of 100 × 10/μL in WBC count, the likelihood of pseudohyperkalemia increased significantly (multiplied by 3.75), suggesting that careful sample handling is crucial for accurate potassium level assessment
Article Synopsis
- The study investigates the effectiveness of new small-molecule compounds targeting topoisomerase II and DNA repair mechanisms in treating castration-resistant prostate cancer (CRPC).
- A new series of azathioxanthone derivatives were developed, with several compounds (WC-A13, WC-A14, WC-A15) showing strong anti-CRPC properties, particularly by downregulating topoisomerase II proteins and causing mitochondrial dysfunction.
- The compounds also triggered specific DNA damage response pathways and exhibited varying effects on Rad51, an important protein involved in DNA repair, highlighting their potential as effective treatments for CRPC.
Background: Depression increases the risk of cardiovascular disease (CVD). The association between antidepressant medications (ADMs) and CVD remains controversial. Hyperlipidemia is a risk factor for CVD.
View Article and Find Full Text PDFConsidering the birefringence of the gain medium, we propose a selection rule for designing cavity configurations that enable the generation of radially and azimuthally polarized laser beams with a low beam quality factor, i.e., high beam quality.
View Article and Find Full Text PDF