[Exploration of transcriptome SSR markers and its application in genetic diversity assessment of Asarum sieboldii].

To explore the genetic diversity of Asarum sieboldii this study developed SSR markers based on transcriptome sequencing results and five populations of A.sieboldii from different regions were used as samples for genetic diversity assessment using software such as GenALEx 6.5, NTSYS 2.

Long non-coding RNA ZFY-AS1 represses periodontitis tissue inflammation and oxidative damage via modulating microRNA-129-5p/DEAD-Box helicase 3 X-linked axis.

A large number of studies have manifested long non-coding RNA (lncRNA) is involved in the modulation of the development of periodontitis, but the specific mechanism has not been fully elucidated. The purpose of this study was to explore the biological function and latent molecular mechanism of lncZFY-AS1 in periodontitis. The results clarified lncZFY-AS1 and DEAD-Box Helicase 3 X-Linked (DDX3X) were up-regulated, but microRNA (miR)-129-5p was down-regulated in periodontitis.

[In-Vivo Noninvasive Measurement of Human Blood Glucose Levels by Mid-Infrared Spectrograph with External CO(2) Laser Source].

Diabetes is a kind of diseases which does harm to people’s health, and the detection of human blood glucose levels utilizing blood samples will result in pain even infection for patients. Thus the in-vivo noninvasive measurement of human blood glucose levels has vital value in clinical diagnosis, detection and therapy, and it also is a very hot research topic with challenging. At present, as to various noninvasive detection methods, the technology based on mid-infrared absorption spectrophotometry with ATR has been gaining increasing attention.

Preparation of 5-fluorouracil-loaded nanoparticles and study of interaction with gastric cancer cells.

Aims: To prepare 5-fluorouracil (5-Fu) nanoparticles with higher encapsulation efficiency and drug loading, and then investigate interaction with the SGC-7901 gastric cancer cell line.

Materials And Methods: Prescription was optimized by orthogonal experiments, the encapsulation efficiency and loading capacity were tested by high- performance liquid chromatography, and inhibition of proliferation by 5-Fu nanoparticles and 5-Fu given to cells for 24, 48 and 72 hours was investigated by methyl thiazolyl tetrazolium assay (MTT). In addition, 5-Fu nanoparticles were labeled by fluorescein isothiocyanate (FITC), and absorption into cells was tested by flow cytometry.

[Effect of nitrogen supply on biomass accumulating and root respiration dynamic changing of Glycyrrhiza uralensis].

This paper aimed to study the effect nitrogen supplying on biomass accumulation and root respiration dynamic change of Glycyrrhiza uralensis and reveal the metabolic pathway of root respiration impact the biomass accumulating of G. uralensis. Six groups of one-year-old G.

Low-bandgap conjugated polymer for high efficient photovoltaic applications.

We investigate the morphological and performance of organic photovoltaics based on blended films of alternating poly(thiophene-phenylene-thiophene) and [6,6]-phenyl-C(71)-butyric acid methyl ester (PC(71)BM). The resulting fine-scale phase separation leads to enhanced performance and the highest power efficiency (6.4% under AM 1.

Preparation of enteric microsphere of oleanolic acid dihemiphthalate sodium by salting-out action using spherical crystallization technique.

Aim: Enteric microspheres were prepared to prevent the interaction of drug with gastric acid and to improve its bioavailability.

Methods: The enteric microspheres with a matrix structure were successfully produced using a spherical crystallization technique. Hydroxypropyl methylcellulose phthalate (HP-55), an enteric material, was coprecipitated with the drug by salting-out effect during the preparation process.

[Investigation and application of powdering technique on oily drug of the traditional Chinese medicine].

To review the development and application of powdering technique on oily drug of the traditional Chinese medicine. There have been numerous methods of powdering technique on oily drug, such as preparing complexation, microcapsule, adsorption by adsorbent, solid lipid nanoparticles, etc. And beta-Cyclodextrin complexation is the most usually operated.

[Preparation of sustained-release nitrendipine microspheres with a solid dispersed structure in liquid system].

Aim: To prepare the sustained-release nitrendipine microspheres with a solid dispersed structure in liquid system.

Methods: The sustained-release nitrendipine microspheres with a solid dispersed structure was prepared in liquid system by combining spherical crystallization technique and solvent deposition method in one step. The resultant microspheres were evaluated for the recovery, micromeritc properties, incorporation efficiency.

Preparation of sustained-release nitrendipine microspheres with Eudragit RS and Aerosil using quasi-emulsion solvent diffusion method.

Sustained-release nitrendipine microspheres were prepared in liquid system by quasi-emulsion solvent diffusion method, in which the Aerosil was employed as an inert dispersing carrier to improve the dissolution rate of nitrendipine, and Eudragit RS as a retarding agent to control the release rate. The resultant microspheres were evaluated for the recovery, bulk density, average particle size, drug loading, and incorporation efficiency. And the factors affecting the formation of microspheres and the drug-release rate were investigated.