Correlation between Tubulointerstitial Lesion and Blood Pressure in Lupus Nephritis Patients: A Pathological, Retrospective Study.

Objective: The objective was to study the influence of pathological factors of glomerular lesion (GL), tubulointerstitial lesion (TIL), and arteriosclerotic lesion on the blood pressure (BP) of lupus nephritis (LN).

Methods: The pathological data and clinical characteristics of 69 LN patients who underwent their first renal biopsy in Chengdu Second People's Hospital from 2012 to 2018 were retrospectively analyzed. The revised 2018 ISN/RPS classification criteria of LN were used to assess the GL and TIL.

Oceanospirillum sediminis sp. nov., Isolated From Coastal Sediment in the Yellow Sea.

A novel Gram-negative, motile, aerobic, spiral-shaped bacterium designated D5, was isolated from a coastal sediment collected in the Yellow Sea. Optimal growth occurred at 30 °C, pH 7.0-8.

Establishment of a dmp based maternal haploid induction system for polyploid Brassica napus and Nicotiana tabacum.

Doubled haploid (DH) technology is used to obtain homozygous lines in a single generation, a technique that significantly accelerates the crop breeding trajectory. Traditionally, in vitro culture is used to generate DHs, but this technique is limited by species and genotype recalcitrance. In vivo haploid induction (HI) through seed is widely and efficiently used in maize and was recently extended to several other crops.

Corrigendum: Aberrant Interhemispheric Functional Connectivity in Diabetic Retinopathy Patients.

[This corrects the article DOI: 10.3389/fnins.2021.

Single-cell multiomics reveals heterogeneous cell states linked to metastatic potential in liver cancer cell lines.

Hepatocellular carcinoma (HCC) is the most common liver cancer with a high rate of metastasis. However, the molecular mechanisms that drive metastasis remain unclear. We combined single-cell transcriptomic, proteomic, and chromatin accessibility data to investigate how heterogeneous phenotypes contribute to metastatic potential in five HCC cell lines.

Casein-hempseed protein complex via cross-link catalyzed by transglutaminase for improving structural, rheological, emulsifying and gelation properties.

In present study, microbial transglutaminase (MTGase) was applied to strengthen the interaction between casein and hempseed protein (HPI) through crosslinking. The structural and functional characteristics of this heteropolymers were investigated. Both homologous and heterologous crosslinking were achieved by adding MTGase in casein-HPI system, and thus enhanced zeta potential, surface hydrophobicity, viscosity, emulsifying and gelation properties of the complex.

ZmCOI2a and ZmCOI2b redundantly regulate anther dehiscence and gametophytic male fertility in maize.

In higher plants, the generation and release of viable pollen from anthers is vital for double fertilization and the initiation of seed development. Thus, the characterization of genes related to pollen development and anther dehiscence in plants is of great significance. The F-box protein COI1 plays a crucial role in the jasmonate (JA) signaling pathway and interacts with many JAZ family proteins in the presence of jasmonoyl-isoleucine (JA-Ile) or coronatine (COR).

Stanniocalcin2 inhibits the epithelial-mesenchymal transition and invasion of trophoblasts via activation of autophagy under high-glucose conditions.

Maternal pregnancy hyperglycemia is often accompanied by placental dysfunction. During placental development, epithelial-mesenchymal transition (EMT) contributes to the transformation of relatively noninvasive trophoblasts into highly invasive extravillous trophoblasts (EVTs). However, the specific role of EMT in placentas under hyperglycemia environments remains relatively unexplored.

New protocol for the R134a cryogen spray cooling assisted 1064-nm laser lipolysis.

Laser lipolysis is a promising body contouring technology. However, the skin tissue could be thermally damaged owing to the laser energy absorption by water, which limits the lipolysis efficiency. To protect skin tissue and improve the lipolysis effect, cryogen spray cooling is introduced and synergized with the pulsed laser irradiation aiming to propose a new therapy protocol.

Simultaneous degradation of p-nitrophenol and reduction of Cr(VI) in one step using microwave atmospheric pressure plasma.

Different physicochemical properties between Cr(VI) and phenolic compounds pose serious challenges for the effective treatment of co-contamination. This study developed an electrodeless high-flow microwave atmospheric plasma jet for the single-step simultaneous degradation of p-nitrophenol (PNP) and reduction of Cr(VI). Following a 15 min treatment with microwave atmospheric pressure plasma, the removal efficiency of Cr(VI) and PNP reached 97.

Health risks and economic losses from cold spells in China.

Background: Cold significantly increases the risk of mortality. However, the health risks associated with cold spells, persistent and extreme cold temperature events, have yet to be investigated in detail.

Methods: Meteorological and mortality data was collated from 280 counties in China from 2013 through 2019.

Single-cell transcriptomic landscape identifies the expansion of peripheral blood monocytes as an indicator of HIV-1-TB co-infection.

Certain circulating cell subsets are involved in immune dysregulation in human immunodeficiency virus type 1 (HIV-1) and tuberculosis (TB) co-infection; however, the characteristics and role of these subclusters are unknown. Peripheral blood mononuclear cells (PBMCs) of patients with HIV-1 infection alone (HIV-pre) and those with HIV-1-TB co-infection without anti-TB treatment (HIV-pre & TB-pre) and with anti-TB treatment for 2 weeks (HIV-pre & TB-pos) were subjected to single-cell RNA sequencing (scRNA-seq) to characterize the transcriptome of different immune cell subclusters. We obtained > 60,000 cells and identified 32 cell subclusters based on gene expression.

The counteraction of anammox community to long-term nitrite stress: Crucial roles of rare subcommunity.

Understanding the temporal dynamics and recovery of anammox community under nitrite stress is critical for successful application of anammox-related processes. Here, the response behaviors of anammox community were investigated to characterize the reactor performance and ecological function under varied levels of nitrite stress (changing from 0, 50, 100, 200 to 0 mg-N/L) across a large temporal scale (588 days). The nitrogen removal rates decreased from 0.

Resist-Free Lithography for Monolayer Transition Metal Dichalcogenides.

Photolithography and electron-beam lithography are the most common methods for making nanoscale devices from semiconductors. While these methods are robust for bulk materials, they disturb the electrical properties of two-dimensional (2D) materials, which are highly sensitive to chemicals used during lithography processes. Here, we report a resist-free lithography method, based on direct laser patterning and resist-free electrode transfer, which avoids unintentional modification to the 2D materials throughout the process.

Astragalus Total Saponins Ameliorate Peritoneal Fibrosis by Promoting Mitochondrial Synthesis and Inhibiting Apoptosis.

Peritoneal fibrosis (PF) is a disease caused by prolonged exposure of the peritoneum to high levels of dialysis fluid. Astragalus total saponins (ATS) is a phytochemical naturally occurring in that has anti-inflammatory and anti-oxidant properties. In this study, we constructed an model of PF using 4.

Aberrant Interhemispheric Functional Connectivity in Diabetic Retinopathy Patients.

Accumulating lines of evidence demonstrated that diabetic retinopathy (DR) patients trigger abnormalities in brain's functional connectivity (FC), whereas the alterations of interhemispheric coordination pattern occurring in DR are not well understood. Our study was to investigate alterations of interhemispheric coordination in DR patients. Thirty-four DR individuals (19 males and 15 females: mean age: 52.

Overstocked Agricultural Produce and Emergency Supply System in the COVID-19 Pandemic: Responses from China.

The spread of COVID-19 has affected not only public health but also agriculture, raising global concerns regarding the food system. As an immediate impact of COVID-19, farmers around the globe have had difficulties with sales, resulting in large amounts of overstocked agricultural products and food loss. This further threatens the livelihood of rural, poor farmers and impacts sustainable production.

New Progress in Improving the Delivery Methods of Bisphosphonates in the Treatment of Bone Tumors.

Bone tumors are tumors that occur in the bone or its accessory tissues, including primary tumors and metastatic tumors. The main mechanism of bisphosphonate is to inhibit the resorption of destructive bone, inhibit the activity of osteoclasts and reduce the concentration of blood calcium. Therefore, bisphosphonates can be used for malignant hypercalcaemia, pain caused by osteolytic bone metastasis, prevention of osteolytic bone metastasis, multiple myeloma osteopathy, improving radiosensitivity and so on.

Diagnostic Value of CD4/CD8 in Scrub Typhus.

Scrub typhus is often misdiagnosed in febrile patients, leading to antibiotic abuse and multiple complications. We conducted a retrospective record review at the Fourth Affiliated Hospital of Guangxi Medical University in China. Data were collected on 52 patients with a confirmed diagnosis of scrub typhus and complete clinical data.

Physiological responses and transcriptome analysis of Spirodela polyrhiza under red, blue, and white light.

Red light (RL) accelerated starch accumulation in S. polyrhiza, but higher protein content under blue light (BL) was associated with the upregulation of most DEGs enriched for specific GO terms and KEGG pathways. Red light (RL) and blue light (BL) greatly influence the growth and physiological processes of duckweed.

Insights into how poly aluminum chloride and poly ferric sulfate affect methane production from anaerobic digestion of waste activated sludge.

Poly aluminum chloride (PAC) and poly ferric sulfate (PFS) are widely used in wastewater treatment and sludge dewatering, resulting in their amounts being accumulated substantially in waste activated sludge (WAS). Till now, however, little information about their influence on WAS digestion is available. This work therefore aims to provide insights into how PAC and PFS affect sludge anaerobic digestion.

Ultrafast Synthesis of I-Rich Lithium Argyrodite Glass-Ceramic Electrolyte with High Ionic Conductivity.

Lithium argyrodites are one of the most promising sulfide electrolytes due to their high ionic conductivity and ductile feature. Among them, Li PS I (LPSI) exhibits better stability against Li metal but a rather low ionic conductivity (only ≈10 S cm ) because of the absence of S /I disorder. Herein, argyrodite Li PS I glass-ceramic electrolytes with high iodine content are synthesized using ultimate-energy mechanical alloying method.