Qnox index for quantification of intraoperative nociception and analgesia: a prospective single-centre validation study.

Background: The Qnox index is a novel monitor to quantify intraoperative nociception based on an electroencephalographic algorithm. We evaluated the ability of the Qnox index to discriminate noxious from non-noxious stimuli, respond to stimuli, and discriminate different levels of analgesia in patients under propofol anaesthesia with neuromuscular block.

Methods: Qnox was compared with heart rate and mean arterial pressure with five designated stimuli: tetanic stimulations without (tetanic 1) and with sufentanil (tetanic 2), skin incision, tracheal intubation, and a non-noxious period.

Intraoperative hypotension is associated with decreased long-term survival in older patients after major noncardiac surgery: Secondary analysis of three randomized trials.

Study Objective: To assess the association of intraoperative hypotension with long-term survivals in older patients after major noncardiac surgery mainly for cancer.

Design: A secondary analysis of databases from three randomized trials with long-term follow-up.

Setting: The underlying trials were conducted in 17 tertiary hospitals in China.

Delirium in older patients given propofol or sevoflurane anaesthesia for major cancer surgery: a multicentre randomised trial.

Background: Delirium is a common and disturbing postoperative complication that might be ameliorated by propofol-based anaesthesia. We therefore tested the primary hypothesis that there is less delirium after propofol-based than after sevoflurane-based anaesthesia within 7 days of major cancer surgery.

Methods: This multicentre randomised trial was conducted in 14 tertiary care hospitals in China.

CircNFIX stimulates the proliferation, invasion, and stemness properties of ovarian cancer cells by enhancing SH3RF3 mRNA stability via binding LIN28B.

We aimed to study the regulatory roles and mechanism of circular nuclear factor IX (circNFIX) in cancer growth and stemness properties of ovarian cancer (OC). CircNFIX and SH3RF3 levels in OC tissues and cells were tested by quantitative real-time PCR. RNase R treatment quantified circNFIX RNA stability.

Exosomal circNFIX promotes angiogenesis in ovarian cancer via miR-518a-3p/TRIM44 axis.

Ovarian cancer (OC) is a gynecological cancer with high mortality. OC-derived exosomal circRNAs can regulate angiogenesis. This study aims to explore the role and mechanism of exosomal circRNA nuclear factor I X (CircNFIX) derived from OC cells in angiogenesis.

Integrative transcriptomic and metabolomic analyses unveil tanshinone biosynthesis in Salvia miltiorrhiza root under N starvation stress.

Salvia miltiorrhiza is a model plant for Chinese herbal medicine with significant pharmacologic effects due to its tanshinone components. Our previous study indicated that nitrogen starvation stress increased its tanshinone content. However, the molecular mechanism of this low nitrogen-induced tanshinone biosynthesis is still unclear.

[Deposition Characteristics of Water-soluble Inorganic Nitrogen and Organic Nitrogen in Atmospheric Precipitation in the Northern Suburbs of Nanjing].

Based on atmospheric precipitation collected in the northern suburbs of Nanjing from 2019 to 2020, the pH, conductivity, and chemical components of precipitation were analyzed. The seasonal variation in pH and conductivity of atmospheric precipitation in the northern suburbs of Nanjing were studied. The pollution levels and deposition characteristics of water-soluble inorganic nitrogen (WSIN) and organic nitrogen (WSON) in precipitation were also analyzed.

[Pollution Characteristics and Sources of Water-soluble Organic Nitrogen in PM in Jiangbei New Area, Nanjing].

The seasonal variation characteristics of water-soluble organic nitrogen (WSON) in PM were analyzed in the Nanjing Jiangbei new area. The relationship between WSON and water-soluble inorganic nitrogen (WSIN) was also discussed. The results showed that the variation range of WSON in PM was 0.

Protein-energy malnutrition worsens hospitalization outcomes of patients with pancreatic cancer undergoing open pancreaticoduodenectomy.

To assess the role of protein-energy malnutrition on perioperative outcomes in patients with pancreatic cancer undergoing open pancreaticoduodenectomy. We conducted a retrospective observational cohort study and investigated patients ≥ 18 years old with pancreatic cancer undergoing open pancreaticoduodenectomy within the National inpatient sample database during 2012-2014. The study population was divided into two groups based on the presence of protein-energy malnutrition.

Intraoperative Intravenous Mannitol Administration Failed to Provide Added Value on Renal Functional Preservation After Partial Nephrectomy in Patients with Chronic Kidney Disease: A Matched Cohort Study.

Previous randomized-controlled trials have demonstrated that intraoperative intravenous mannitol administration shows no added value on renal functional preservation after partial nephrectomy (PN) in patients with normal renal function. However, the renoprotective effect of mannitol has not been fully evaluated in patients with preoperative chronic kidney disease (CKD). This was a retrospective cohort study with propensity score matching.

TRIM44 facilitates ovarian cancer proliferation, migration, and invasion by inhibiting FRK.

Ovarian cancer (OC) is the leading cause of gynecologic cancer-related death in the world. Accumulating evidence indicated the important role of TRIM44 in cancer development. However, how TRIM44 displays in OC and the underlying mechanism remained unclear.

[Characteristics and Sources of Water-soluble Ion Pollution in PM in Winter in Shenyang].

In order to explore the characteristics of PM and water-soluble ions in Shenyang in winter, the URG-9000D online monitoring system was used to continuously sample PM and gas components during 2018. The results indicated that the average concentration of PM in Shenyang during the sampling period was 80.67 μg·m, and the total water-soluble ion concentration ranged from 2.

Preoperative intravenous rehydration for patients with pheochromocytomas and paragangliomas: is it necessary? A propensity score matching analysis.

Background: Preoperative intravenous rehydration for patients with pheochromocytomas and paragangliomas (PPGLs) is widely used in many medical centers, but its usefulness has not been well evaluated. The objective of this study was to compare the perioperative hemodynamics and early outcome between patients who received preoperative intravenous rehydration and those without for resection of PPGLs.

Methods: In this retrospective propensity score-matched cohort study, the data of patients who underwent surgery for PPGLs were collected.

[Size Distribution of Particulate Chemical Components in Nanjing Jiangbei New Area].

In order to explore the pollution characteristics of the chemical components of atmospheric particulate matter in Nanjing Jiangbei New Area, size-resolved samples were collected from 2013 to 2014. The size distribution and seasonal variation of the chemical components of the particles were studied. The results showed that the total concentration of nine water-soluble ions in fine particles was higher in autumn and winter than in spring and summer, while the concentration of coarse particles was highest in winter.

[Characterization of AOX family members from Aquilaria sinensis and their responses to wounding].

Aquilaria sinensis is a typical inducible medicinal plant, that can produce agarwood only after it is wounded by external stimuli. Alternative oxidase(AOX) is one of the terminal oxidases of the plant mitochondrial electron transport, which plays an important role in plants' response to environmental stress. In order to reveal the physiological function of AOX gene in the process of agarwood formation from A.

Transcriptome changes induced by in cervical cancer cells .

Runt-related transcription factor 3 () is a member of Runt domain family that is known to play key roles in various different types of tumor. It was recently demonstrated that may also be associated with cervical cancer. The aim of the present study was to investigate the potential association between transcriptome changes and expression in cervical cancer.

[Establishment and Characteristics of an Artificial Ammonia Emissions Inventory in Jiangsu Province from 2013 to 2017].

According to activity level data of various ammonia emission sources in Jiangsu Province, using a reasonable inventory calculation method and emission factor, an ammonia emission inventory in Jiangsu Province from 2013 to 2017 was established, and the trend of anthropogenic ammonia emissions over these years was analyzed. The distribution characteristics of anthropogenic ammonia emissions and emission intensity in Jiangsu Province were analyzed using ArcGIS software. The results showed that the ammonia emissions in Jiangsu Province decreased from 624.

[Distribution and Treatment of Antibiotics in Typical WWTPs in Small Towns in China].

As a new, persistent pollutant in the environment, antibiotics are one of the most important pollutants in sewage treatment plants. The objective of this work was to investigate the concentration distribution and removal efficiency of antibiotics for three typical wastewater treatment technologies applied in small towns (CASS, A/O, and Orbal oxidation ditch) using solid phase extraction-liquid chromatography-tandem mass spectrometry. Sixteen typical antibiotics, including four tetracyclines, three -lactams, four macrolides, three quinolones, and two sulfonamides, were analyzed in the influent and effluent.

Newly discovered Late Triassic Baqing eclogite in central Tibet indicates an anticlockwise West-East Qiangtang collision.

The Triassic eclogite-bearing central Qiangtang metamorphic belt (CQMB) in the northern Tibetan Plateau has been debated whether it is a metamorphic core complex underthrust from the Jinsha Paleo-Tethys or an in-situ Shuanghu suture. The CQMB is thus a key issue to elucidate the crustal architecture of the northern Tibetan Plateau, the tectonics of the eastern Tethys, and the petrogenesis of Cenozoic high-K magmatism. We here report the newly discovered Baqing eclogite along the eastern extension of the CQMB near the Baqing town, central Tibet.

[Aerobic Degradation Characteristics of the Quinoline-Degrading strain sp. and Its Bioaugmentation in Coking Wastewater].

Quinoline is one of the common refractory organic pollutants in coking wastewater. An aerobic bacterial strain KDQ3 capable of utilizing quinoline as the sole source of carbon, nitrogen and energy was isolated from activated sludge of a coking wastewater treatment plant. The morphological properties and the 16S rDNA sequence identified KDQ3 as sp.

Stability Study of Cervical Specimens Collected by Swab and Stored Dry Followed by Human Papillomavirus DNA Detection Using the cobas 4800 Test.

Safer, more convenient methods for cervical sample collection and storage are necessary to facilitate human papillomavirus (HPV) DNA testing in low-resource settings. Our study aimed to evaluate the stability of cervical specimens collected with dry swabs and stored dry, compared to liquid-based cytology (LBC) samples, as detected by HPV DNA testing. Women with abnormal cytological findings or HPV-positive results at colposcopy were recruited from the West China Second University Hospital, Sichuan University, between October 2013 and March 2014.

[Biodiversity of Thiocyanate-degrading Bacteria in Activated Sludge from Coking Wastewater].

Thiocyanate (SCN) is one of the main sources of COD in coking wastewater, and SCN removal efficiency of the aerobic unit impacts the requirement of discharging standard. Microbial population in the activated sludge plays an important role in SCN removal of coking wastewater treatment. However, the community structure has rarely been reported.