Background: Screen time encompasses activities conducted on digital devices, including traditional devices such as televisions and computers, as well as modern devices like smartphones, tablets, and other digital screens. Excessive screen time among children has been linked to a heightened likelihood of engaging in high-risk problem behaviours. This study aimed to quantify the prevalence of excessive screen time and delve into its correlation with problem behaviours among school-aged children in Fujian, thereby gaining insight into the prevalence and trends within this region.
View Article and Find Full Text PDFCollagenases are responsible for collagen degradation, resulting in shrimp muscle softening after death. In this study, biochemical characteristics of collagenases purified from hepatopancreas (CPH) and muscle (CPM) of Litopenaeus vannamei were comparatively investigated. Changes of enzyme activity in shrimp hepatopancreas and muscle presented totally different tendencies, which decreased and increased respectively.
View Article and Find Full Text PDFThe coexistence of surfactants and antibiotics in aquatic environments can potentially trigger combined toxic effects on aquatic organisms. Unfortunately, the effects of these joint toxins and the corresponding mechanism remain unclear. In this study, we performed individual and combined toxicity experiments involving surfactants and antibiotics.
View Article and Find Full Text PDFAlthough the association between heavy metals in human and the development of metabolic syndrome (MetS) have been extensively studied, the pathogenic mechanism of MetS affected by metals is not clear to date. In this study, a predictive model was developed with machine learning base on the large-scale dataset. These proposed models were evaluated via comparatively analysis of their accuracy and robustness.
View Article and Find Full Text PDFMetal halide perovskites show promise for next-generation light-emitting diodes, particularly in the near-infrared range, where they outperform organic and quantum-dot counterparts. However, they still fall short of costly III-V semiconductor devices, which achieve external quantum efficiencies above 30% with high brightness. Among several factors, controlling grain growth and nanoscale morphology is crucial for further enhancing device performance.
View Article and Find Full Text PDFThe toxicity of chemical mixtures may be misestimated, as the assessment of individual chemicals may not adequately reflect their combined toxic effects. However, numerous combinations of chemicals and various interactions make it impossible to measure all possible mixtures. Computational toxicology can help to mitigate this issue, particularly with new methodologies that rely upon alternatives to animal testing.
View Article and Find Full Text PDFLayered halide perovskites have garnered significant interest due to their exceptional optoelectronic properties and great promises in light-emitting applications. Achieving high-performance perovskite light-emitting diodes (PeLEDs) requires a deep understanding of exciton dynamics in these materials. This review begins with a fundamental overview of the structural and photophysical properties of layered halide perovskites, then delves into the importance of dimensionality control and cascade energy transfer in quasi-2D PeLEDs.
View Article and Find Full Text PDFThe liver has multiple functions such as detoxification, metabolism, synthesis and storage. Folate is a water-soluble vitamin B, which participates in one-carbon transfer reactions, maintains methylation capacity and improves oxidative stress. Folic acid is a synthetic form commonly used as a dietary supplement.
View Article and Find Full Text PDFA flame-retardant and hydrophobic coating was deposited on the surface of the cotton fabric via a two-step spray deposition technique. Specifically, the coating was composed of flame-retardant component (guanidine phosphate) and hydrophobic components (Ti-MOF and bis(3-aminopropyl)-terminated poly(dimethylsiloxane) (PDMS)) and crosslinked with glutaraldehyde. The limiting oxygen index (LOI) of the coated cotton fabrics increased from 18.
View Article and Find Full Text PDFBackground: Falls are the most common injuries in older adults, and fall prevention is one of the primary measures to achieve healthy aging. Self-management refers to the measures taken by individuals to avoid various adverse factors and health damage to protect and promote their health. This study aimed to explore the factors and measures of self-managed fall prevention among community-dwelling older adults.
View Article and Find Full Text PDFA mounting body of evidences suggests that patients with chronic heart failure (HF) frequently experience cognitive impairments, but the neuroanatomical mechanism underlying these impairments remains elusive. In this retrospective study, 49 chronic HF patients and 49 healthy controls (HCs) underwent brain structural MRI scans and cognitive assessments. Cortical morphology index (cortical thickness, complexity, sulcal depth and gyrification) were evaluated.
View Article and Find Full Text PDFHerein, a new electrochemiluminescence (ECL) biosensor was constructed with highly efficient polymerized carbon dots (PCDs) as ECL emitter and the improved localized catalytic hairpin assembly (L-CHA) as signal amplifier for ultrasensitive detection of microRNA-222 (miRNA-222). Impressively, compared to the traditional carbon dots with inefficient blue region ECL emission, PCDs with N, O co-dope and large conjugated π-system showed high electrical conductivity, narrow band gap and strong radiative transition, which could exhibit high ECL efficiency to improve the sensitivity of detection and long wavelength ECL emission to achieve deep tissue penetration for reducing biological damage. Furthermore, the trace target miRNA-222 could be efficiently converted into large amounts of output DNA labelled with the quencher dopamine (S-DA) through the L-CHA reaction to significantly enhance the target amplification efficiency for further improving the sensitivity of detection.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
July 2024
Hepatocellular carcinoma (HCC) is the most prevalent type of primary liver cancer, accounting for the overwhelming majority of malignant liver tumors. Therefore, how to effectively prevent and cure HCC has become a research hotspot. Many studies have shown that arenobufagin can induce apoptosis, ferroptosis, and autophagy of tumor cells.
View Article and Find Full Text PDFNanoplastics (NPs, diameter <1 μm) not only have toxicity but also change the toxicity of other pollutants in water. To date, the nanopolystyrene (nano-PS) size effect and its combined toxicity with halogenated polycyclic aromatic hydrocarbons (HPAHs) remain unclear. In this study, the single toxicity, combined toxicity, and mode of action of the binary mixture of polystyrene (PS) and HPAH were examined.
View Article and Find Full Text PDFSurface plasmon resonance microscopy (SPRM), based on the scattering of single molecules at the interface, is a highly efficient analytical platform widely used in the fields of biology and chemistry. Due to the interference scattering, the imaging pattern exhibits typical parabolic tail and phase transition features, providing a quantitative means of observing the changes in the physical and chemical properties of single molecules. In this work, we reported another unique asymmetric parabolic distribution pattern resulting from polarization conversion in the experiment based on SPRM.
View Article and Find Full Text PDFBroader spectra, lower reflectivity and higher reliability are the performance requirements for broadband antireflective (BBAR) films. In this work, a BBAR film structure was proposed, which maintains extremely low reflectivity, ultra-wide spectra, low polarization sensitivity and practical reliability. The BBAR film consists of a dense multilayer interference stack on the bottom and a nano-grass-like alumina (NGLA) layer with a gradient low refractive index distribution on the top.
View Article and Find Full Text PDFHerein, the novel alloyed silver gold sulfur quantum dots (AgAuS QDs) with highly efficient near-infrared (NIR) electrochemiluminescence (ECL) emission at 707 nm were successfully prepared to construct a biosensing platform for ultrasensitive detection of microRNA-222 (miRNA-222). Interestingly, AgAuS QDs revealed excellent ECL efficiency (34.91%) compared to that of AgS QDs (10.
View Article and Find Full Text PDFOptimizing the atomic layer deposition (ALD) process of films is particularly important in preparing multilayer interference films. In this work, a series of AlO/TiO nano-laminates with a fixed growth cycle ratio of 1:10 were deposited on Si and fused quartz substrates at 300 °C by ALD. The optical properties, crystallization behavior, surface appearance and microstructures of those laminated layers were systematically investigated by spectroscopic ellipsometry, spectrophotometry, X-ray diffraction, atomic force microscope and transmission electron microscopy.
View Article and Find Full Text PDFAs emerging environmental contaminants, cosmetic and personal care additives (CPCAs) may have less oversight than other consumer products. Their continuous release and pseudopersistence could cause long-term harm to the aquatic environment. Since CPCAs generally exist in the form of mixtures in the environment, prediction and analysis of their mixture toxicity are crucial for ecological risk assessment.
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